Breast density, as assessed by mammography, reflects breast tissue composition. Breast epithelium and stroma attenuate x-rays more than fat and thus appear light on mammograms while fat appears dark. In this review, we provide an overview of selected areas of current knowledge about the relationship between breast density and susceptibility to breast cancer. We review the evidence that breast d...

Objective Increased mammographic breast density is a well-established risk factor for breast cancer development, regardless of age or ethnic background. The current gold standard for categorizing breast density consists of a radiologist estimation of percent density according to the American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS) criteria. This study compa...

OBJECTIVE To compare automated volumetric breast density measurement (VBDM) with radiologists' evaluations based on the Breast Imaging Reporting and Data System (BI-RADS), and to identify the factors associated with technical failure of VBDM. MATERIALS AND METHODS In this study, 1129 women aged 19-82 years who underwent mammography from December 2011 to January 2012 were included. Breast dens...

Although there has been much research on the factors associated with breast density, most studies did not include Hispanic women or relied on semiquantitative methods of assessing density. Using data from the Chicago Breast Health Project, which targeted Hispanic women and assessed density quantitatively using full-field digital mammography, we assessed cross-sectional associations of breast ca...

BACKGROUND Benign breast disease and high breast density are prevalent, strong risk factors for breast cancer. Women with both risk factors may be at very high risk. METHODS We included 42818 women participating in the Breast Cancer Surveillance Consortium who had no prior diagnosis of breast cancer and had undergone at least one benign breast biopsy and mammogram; 1359 women developed incide...