Mortality after intravenous challenge with 10(4) Cryptococcus neoformans demonstrated that doubly immunodeficient beige athymic (bg/bg nu/nu) mice were more susceptible to systemic cryptococcosis than either bg/bg or nu/nu mice. Infected bg/bg nu/nu mice also had a shortened lifespan compared with their bg/bg nu/+ littermates. Beige athymic (bg/bg nu/nu) but not bg/bg nu/+mice developed cryptoc...

Abstract Sr-substitution in the crystal structure of bredigite has been studied detail. Samples a hypothetical solid-solution series with nominal composition Ca 7-x Sr x Mg[SiO 4 ] (x = 0, 2, …,7) have prepared from sinter reactions temperature range between 1275 and 1325 °C characterized using powder single-crystal X-ray diffraction. Synthesis runs 1 resulted compounds increasing contents, for...

Background: Bioactive glass (BG) nanoparticles are amongst the most promising class of biomaterials for hard tissue regeneration because of their distinctive properties of rapid bone bonding, controlled biodegradability and their ability to stimulate new bone growth. Despite the vast interest in BG scaffolds in medical applications, the synthesis of bioactive glass nanoparticles is still facing...