نتایج جستجو برای: bromocriptine mesylate

تعداد نتایج: 4670  

2013
Olakunle James Onaolapo Adejoke Yetunde Onaolapo

This study set out to assess the neurobehavioral effects of subchronic, oral bromocriptine methanesulfonate using the open field and the Y-maze in healthy male mice. Sixty adult Swiss albino mice were assigned into three groups. Controls received normal saline, while test groups received bromocriptine methanesulfonate at 2.5 and 5 mg/kg/day, respectively, for a period of 21 days. Neurobehaviora...

Journal: :Rhode Island medical journal 2013
Anthony Cincotta

VeroScience is a biotechnology company in Tiverton, Rhode Island, focused on the development of therapies and products to improve human health. The company has a strong pipeline of metabolic disease products and therapies for immunological disorders. A major platform technology of the company, Circadian Neuroendocrine Resetting Therapy, is utilized as a generator of multiple therapeutic strateg...

2012
J. Michael Gaziano Anthony H. Cincotta Aaron Vinik Lawrence Blonde Nancy Bohannon Richard Scranton

BACKGROUND Bromocriptine-QR (a quick-release formulation of bromocriptine mesylate), a dopamine D2 receptor agonist, is a US Food and Drug Administrration-approved treatment for type 2 diabetes mellitus (T2DM). A 3070-subject randomized trial demonstrated a significant, 40% reduction in relative risk among bromocriptine-QR-treated subjects in a prespecified composite cardiovascular (CV) end poi...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1990
P Haider

Bromocriptine, the active ingredient of Parlodel is a specific dopamine receptor agonist available for use in clinical practice. It has been successfully used in the treatment of hyperprolactinemia with associated amenorrhea, galactorrhea and infertility; in the inhibition of postpartum lactation; acromegaly and in Parkinson's disease. Its role in obstetrics and gynaecology is strategic since i...

2008
R. Makdassi B. de Cagny

Prof. A. Fournier, Service de Néphrologie, Hôpital Sud, F-80054 Amiens Cedex 1 (France) Dear Sir, Bromocriptine mesylate (Parlodel®, San-doz) is a prolactin secretion inhibitor commonly used for suppression of puerperal lactation [1]. It is an ergoalkaloid derivate in which hydrogenation suppresses the usual α-adrenergic vasoconstrictive effect of these derivates. Furthermore, it is a vasodilat...

Journal: :Journal of neurophysiology 2003
Nestor G Davila Laura J Blakemore Paul Q Trombley

The glomerular layer of the olfactory bulb (OB) contains synaptic connections between olfactory sensory neurons and OB neurons as well as connections among OB neurons. A subpopulation of external tufted cells and periglomerular cells (juxtaglomerular neurons) expresses dopamine, and recent reports suggest that dopamine can inhibit olfactory sensory neuron activation of OB neurons. In this study...

2015
JB Celik A Duman O Arun IO Onal O Ilban AE Sonmez

Introduction Bromocriptine Mesylate (BC) is an ergot derivative with potent dopamine receptor agonist activity. It is licensed to reduce plasma levels of prolactin. BC has central nervous effects, and is used in patients with Parkinson’s disease. There are few randomized controlled trials with BC conducted in moderate brain injury (BI) with conflicting results (1). We aim to present our single ...

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