We report the case of a 59 year old woman who developed cough, dyspnoea and fever with patchy migratory airspace infiltrates, 2 months after right breast radiation therapy for breast carcinoma. Lung infiltrates were initially localized in the irradiated area and spread to the contralateral lung. Lung biopsy, performed in an unirradiated area of the contralateral lung 9 months after completion o...

disease involving manyorgan systems. Amongthem, respiratory involvement is frequent including pleuritis, interstitial pneumonitis/flbrosis, and bronchiolitis; the latter two can be life threatening. Obliterative bronchiolopathies in the general population are classified into 3 categories : bronchiolitis obliterans (BO ; obliterative bronchiolitis, OB), diffuse panbronchiolitis (DPB) and bronchi...

The disease concept of idiopathic BOOP has emerged from a study of many open lung biopsy cases of diffuse infiltrative lung disease. The histopathologic features of idiopathic BOOP have several components: bronchiolitis obliterans, organizing pneumonia, accumulation of foamy cells in the peripheral air spaces, and interstitial infiltration of mononuclear cells. These pathologic findings are non...

Bronchiolitis obliterans organizing pneumonia (BOOP) is increasingly recognized as an important cause of diffuse infiltrative lung disease. It is a diagnostic consideration in patients with a febrile flu-like illness of a few weeks' duration and a roentgenogram showing bilateral patchy infiltrates that are not responsive to a typical course of antibiotics. It is defined as granulated tissue plu...

Bronchiolitis obliterans organizing pneumonia (BOOP) is a diffuse infiltrative pulmonary disorder that has an insidious onset. The patient often presents with flu-like symptoms and radiological findings showing bilateral patchy infiltrates. Histological features show fibromyxoid connective tissue plugs that are evenly spaced in small distal airways and alveolar spaces. Treatment for BOOP is cor...

HSCT: Hematopoietic Stem Cell Transplantation; GVHD: GraftVersus-Host-Disease; DAH: Diffuse Alveolar Hemorrhage; ARDS: Acute Respiratory Distress Syndrome; RSV: Respiratory Syncytial Virus; CMV: Cytomegalovirus; HLA: Human Leucocyte Antigen; PCR: Polymerase Chain Reaction; IPS: Idiopathic Pneumonia Syndrome; OP: Organizing Pneumonia; BOOP: Bronchiolitis Obliterans Organizing Pneumonia; COP: Cry...

5-Aminosalicylate agents are the main therapeutic agents for ulcerative colitis. Balsalazide is a prodrug of 5-aminosalicylate and has fewer side effects than the other 5-aminosalicylate agents. Pulmonary complications resembling granulomatosis with polyangiitis in ulcerative colitis are extremely rare. Here, we report a patient with ulcerative colitis on balsalazide presenting respiratory symp...