نتایج جستجو برای: bulked segregant analysis

تعداد نتایج: 2824314  

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1999
M Knight A N Miller C N Patterson C G Rowe G Michaels D Carr C S Richards F A Lewis

Both snail and parasite genes determine the susceptibility of the snail Biomphalaria glabrata to infection with the trematode Schistosoma mansoni. To identify molecular markers associated with resistance to the parasite in the snail host, we performed genetic crosses between parasite-resistant and -susceptible isogenic snails. Because resistance to infection in adult snails is controlled by a s...

2012
Sanzhen Liu Cheng-Ting Yeh Ho Man Tang Dan Nettleton Patrick S. Schnable

Bulked segregant analysis (BSA) is an efficient method to rapidly and efficiently map genes responsible for mutant phenotypes. BSA requires access to quantitative genetic markers that are polymorphic in the mapping population. We have developed a modification of BSA (BSR-Seq) that makes use of RNA-Seq reads to efficiently map genes even in populations for which no polymorphic markers have been ...

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