Total synthesis of largamide H has been completed, utilising the oxidative elimination reaction of enantiomerically pure 2-amino-3-(phenylselenyl)butanoic acid residues to stereospecifically install both (Z)- and (E)-2,3-dehydro-2-aminobutanoic moieties.

In the crystal structure of the title compound, C(11)H(11)FO(2), the methine CH forms an intra-molecular hydrogen bond with the carboxyl- O atom. The mol-ecules form dimers through hydrogen bonding between carboxyl- groups. These dimers are linked to each other by C-H⋯O contacts between the benzene and carbonyl groups of adjoining mol-ecules. In addition, there are weak inter-molecular C-H⋯F co...

The title compound, C(11)H(15)NO(6)S, features a distorted tetra-hedral geometry for the S atom. One of the sulfonamide O atoms is approximately coplanar with the benzene ring [C-C-S-O torsion angle = -160.81 (7)°], whereas the other lies well below the plane [C-C-S-O = -29.66 (8)°]. In the crystal, O-H⋯O and C-H⋯O hydrogen bonds link the mol-ecules into chains parallel to the b axis.

In the title compound, C(12)H(17)NO(4)S(2), the carboxyl groups link the mol-ecules into centrosymmetric dimers through O-H⋯O hydrogen bonds. An N-H⋯O hydrogen bond between the NH group of the l-methio-nine unit and a neighbouring carboxyl group, together with a complementary C-H⋯O contact to one O atom of the sulfonyl group, link the dimers into one-dimensional chains along the crystallographi...

In the title compound, C(12)H(15)NO(4), the butyric acid group has a stretched trans conformation. The dihedral angle between the phenyl ring and the oxycarb-oxy-amino N-(C=O)-O-C plane is 56.6 (2)°. In the crystal, an inversion dimer is formed by a pair of O-H⋯O hydrogen bonds. The dimers are further linked by N-H⋯O hydrogen bonds between amide groups, forming a tape along the b axis.

Analysis of volatiles from rumen digesta by gas chromatography linked antennogram recordings from Stomoxys calcitrans (L) (Diptera: Muscidae) antennal receptor cells revealed about 30 electrophysiologically active constituents, the most important of which is dimethyl trisulphide with a sensory threshold in the femtogram range. The behavioural responses of S. calcitrans to five chemostimulants (...

Smokers or people undergoing nicotine replacement therapy excrete approximately 10% of the nicotine dose as 4-oxo-4-(3-pyridyl)butanoic acid (keto acid) and 4-hydroxy-4-(3-pyridyl)butanoic acid (hydroxy acid). Previously, these acids were thought to arise by secondary metabolism of the major nicotine metabolite cotinine, but our data did not support this mechanism. Therefore, we hypothesized th...

A Major role in oxidation kinetics is to determine the reaction mechanism that comprise chemical reaction. In present paper we derived rate law for and recognized order of reaction, give equation, calculate constant. Identify product this reaction.The 2-Amino-4-methyl thio-butanoic acid by Quinaldinium Fluorochromate was studied 50-50 (v/v) selected hydrophilic solvent medium at 308 Kelvin. The...

Sleep symptoms are associated with weight gain and cardiometabolic disease. The potential role of diet has been largely unexplored. Data from the 2007-2008 National Health and Nutrition Examination Survey (NHANES) were used (n = 4552) to determine which nutrients were associated with sleep symptoms in a nationally representative sample. Survey items assessed difficulty falling asleep, sleep mai...