نتایج جستجو برای: c dubliniensis

تعداد نتایج: 1056745  

Journal: :Journal of clinical microbiology 2003
Elaine Blignaut Claude Pujol Sophie Joly David R Soll

Candida dubliniensis is a yeast species that has only recently been differentiated from Candida albicans. C. dubliniensis colonization was initially associated with human immunodeficiency virus (HIV)-positive individuals. Because of the large proportion of AIDS patients in South Africa, we tested the generality of this association by assessing the prevalence of C. dubliniensis colonization amon...

Journal: :Genome research 2009
Andrew P Jackson John A Gamble Tim Yeomans Gary P Moran David Saunders David Harris Martin Aslett Jamie F Barrell Geraldine Butler Francesco Citiulo David C Coleman Piet W J de Groot Tim J Goodwin Michael A Quail Jacqueline McQuillan Carol A Munro Arnab Pain Russell T Poulter Marie-Adèle Rajandream Hubert Renauld Martin J Spiering Adrian Tivey Neil A R Gow Barclay Barrell Derek J Sullivan Matthew Berriman

Candida dubliniensis is the closest known relative of Candida albicans, the most pathogenic yeast species in humans. However, despite both species sharing many phenotypic characteristics, including the ability to form true hyphae, C. dubliniensis is a significantly less virulent and less versatile pathogen. Therefore, to identify C. albicans-specific genes that may be responsible for an increas...

Journal: :Medical principles and practice : international journal of the Kuwait University, Health Science Centre 2005
Suhail Ahmad Eiman Mokaddas Noura Al-Sweih Zia U Khan

OBJECTIVE This study was carried out to characterize Candida dubliniensis using phenotypic and molecular methods and to determine the occurrence of C. dubliniensis in clinical specimens in Kuwait. MATERIALS AND METHODS A total of 880 clinical specimens for isolation of fungi were processed according to standard procedures. Of these, 390 germ-tube-positive clinical isolates of Candida species ...

2010
Vuyisile S. Thibane Johan L. F. Kock Ruan Ells Pieter W. J. van Wyk Carolina H. Pohl

The effect of marine polyunsaturated fatty acids on biofilm formation by the human pathogens Candida albicans and Candida dubliniensis was investigated. It was found that stearidonic acid (18:4 n-3), eicosapentaenoic acid (20:5 n-3), docosapentaenoic acid (22:5 n-3) and docosahexaenoic acid (22:6 n-3) have an inhibitory effect on mitochondrial metabolism of both C. albicans and C. dubliniensis ...

Journal: :Journal of clinical microbiology 1999
M A Jabra-Rizk W A Falkler W G Merz J I Kelley A A Baqui T F Meiller

The binding of microorganisms to each other and oral surfaces contributes to the progression of microbial infections in the oral cavity. Candida dubliniensis, a newly characterized species, has been identified in human immunodeficiency virus-seropositive patients and other immunocompromised individuals. C. dubliniensis phenotypically resembles Candida albicans in many respects yet can be identi...

Journal: :Microbiology 2004
Gary Moran Cheryl Stokes Sascha Thewes Bernhard Hube David C Coleman Derek Sullivan

Candida dubliniensis is a pathogenic yeast species closely related to Candida albicans. However, it is less frequently associated with human disease and displays reduced virulence in animal models of infection. Here comparative genomic hybridization was used in order to assess why C. dubliniensis is apparently less virulent than C. albicans. In these experiments the genomes of the two species w...

Journal: :Infection and immunity 2001
K C Hazen J G Wu J Masuoka

Although Candida dubliniensis is a close genetic relative of Candida albicans, it colonizes and infects fewer sites. Nearly all instances of candidiasis caused by C. dubliniensis are restricted to the oral cavity. As cell surface hydrophobicity (CSH) influences virulence of C. albicans, CSH properties of C. dubliniensis were investigated and compared to C. albicans. Growth temperature is one fa...

Journal: :Japanese journal of infectious diseases 2005
Hossein Mirhendi Koichi Makimura Kamiar Zomorodian Nobuko Maeda Tomoko Ohshima Hideyo Yamaguchi

Candida dubliniensis is a novel Candida spp. that is similar to Candida albicans with respect to several phenotypic characteristics. However, they differ from each other with respect to epidemiology, pathogenesis, and the rapid development of resistance to fluconazole. In the present study, we used a single-enzyme PCR-restriction fragment length polymorphism (RFLP) technique to differentiate C....

Journal: :Journal of clinical microbiology 2004
Zia U Khan Suhail Ahmad Eiman Mokaddas Rachel Chandy

Isolates of Candida dubliniensis may be misidentified as Candida albicans in microbiological laboratories if only the germ tube and/or the chlamydospore test is used for identification to the species level. In this study, we have evaluated the efficacy of tobacco agar for the differentiation of C. dubliniensis from C. albicans. On this medium at 28 degrees C, all 30 C. dubliniensis isolates pro...

Journal: :Journal of clinical microbiology 1998
W R Kirkpatrick S G Revankar R K Mcatee J L Lopez-Ribot A W Fothergill D I McCarthy S E Sanche R A Cantu M G Rinaldi T F Patterson

Candida dubliniensis has been associated with oropharyngeal candidiasis in patients infected with human immunodeficiency virus (HIV). C. dubliniensis isolates may have been improperly characterized as atypical Candida albicans due to the phenotypic similarity between the two species. Prospective screening of oral rinses from 63 HIV-infected patients detected atypical dark green isolates on CHRO...

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