Mass changes in the incorporation of linoleic (C18:2), eicosapentaenoic (C20:5) and docosahexaenoic (C22:6) acids in human blood platelet phospholipids were induced by incubating the cells and these fatty acids complexed to albumin. The remodelling of [14C]C18:2, [14C]C20:5 and [14C]C22:6 in classes, subclasses and molecular species of platelet phospholipids was studied in resting and thrombin-...

We analyzed clinical and pathological disease in 2 peripheral myelin protein-22 (PMP22) overexpressing mouse models for 1.5 years. C22 mice have 7 and C3-PMP mice have 3 to 4 copies of the human PMP22 gene. C3-PMP mice showed no overt clinical signs at 3 weeks and developed mild neuromuscular impairment; C22 mice showed signs at 3 weeks that progressed to severe impairment. Adult C3-PMP mice ha...

In this study, we have employed graphene oxide as a matrix to simultaneously and directly quantify serum nonesterified and esterified fatty acids (FAs) using matrix-assisted laser/desorption ionization-Fourier transform ion cyclotron resonance mass spectrometry (MALDI-FTICR MS). Twelve serum nonesterified FAs combined with their individual esterified FAs (i.e., C16:0, C16:1, C18:0, C18:1, C18:2...

The steady-state activity of the Ca(2+)-ATPase of skeletal muscle sarcoplasmic reticulum (SR) is low when reconstituted into bilayers of the long-chain phosphatidylcholines dierucyl phosphatidylcholine [di(C22:1)PC] or dinervonyl phosphatidylcholine [di(C24:1)PC]. In di(C24:1)PC the ATPase binds a single Ca2+ ion, whereas in di(C22:1)PC it binds two, as in the native SR [Starling, East and Lee ...

The Texas citrus industry in the Rio Grande Valley experiences periodic droughts. During such times, water restrictions from the Amistad and Falcon Reservoirs can reduce water available for agriculture. Irrigation in this region is primarily surface waters from the Rio Grande where citrus orchards are flood irrigated. Irrigation practices that use less water are being explored and evaluated. ...

1-Palmitoyl phosphatidylcholines (1-palmitoyl PCs), in which the 2-position was occupied respectively by C10:0, C12:0, C14:0, C14:1, n-7, C16:0, C16:1, n-7, C18:0, C18:1(t), n-9, C18:1, n-9, C18:2, n-6, C18:3, N-3, C18:3, n-6, C18:3(5t,9,12), C22:0, C22:1, n-9, C22:2, n-6, C22:3, n-3, C22:4, n-6, C22:5, n-6 or C22:6, n-3 fatty acids, were studied as monolayer films at the air/water interface. R...