To address the means by which diversity of neuronal morphology is generated, we have isolated and characterized naturally occurring variants of rat PC12 pheochromocytoma cells that exhibit altered neurite outgrowth properties in response to nerve growth factor (NGF). We describe here a PC12 cell sub-clone, designated PC12-clone 41 (PC12-C41), that displays significant increases in neurite abund...

BACKGROUND In human arteries, angiotensin-converting enzyme (ACE) inhibitors incompletely block the production of angiotensin (Ang) II from Ang I. This ACE-independent production of Ang II appears to be caused by serine proteases, one of which presumably is chymase. However, several serine proteases may produce Ang II, and the exact role of chymase in the vascular production of Ang II has never...

We have obtained lowand medium-resolution optical spectra of 20 candidate young low-mass stars and brown dwarfs in the nearby Chamaeleon II dark cloud, using the Magellan Baade telescope. We analyze these data in conjunction with near-infrared photometry from the 2-Micron All Sky Survey. We find that one target, [VCE2001] C41, exhibits broad Hα emission as well as a variety of forbidden emissio...

Bacterial cellulose (BC) exhibits unique properties such as high purity compared to plant-based cellulose; however, commercial production of BC has remained a challenge, primarily due to the strain properties of cellulose-producing bacteria. Herein, we developed a functional and stable BC production system in genetically modified (GM) Escherichia coli by recombinant expression of both the BC sy...

In general, FeCrAl alloys are faced with the separation of high-chromium solid solution into α and α′ phases. For Fe-25Cr-5Al-RE alloy, it is imperative to investigate structure morphology their effect on alloy’s mechanical properties. this paper, XRD used reveal presence Based data, Rietveld refinement combined quantitative texture analysis carried out determine lattice constants harmonic coef...

I%e goal of this architecture paper is to describe a more eficient and e~ective standardized framework for distributing information in a networked or web-based environment. 7iiis architecture provides afiamework so many diverse networked applications can work in a collaborative environment sharing data and displays. Technologies such as CORBA, DCOM, and RMI provide the mechanics for communicati...

The hepatitis delta virus ribozyme is a small, self-cleaving RNA with a compact tertiary structure and buried active site that is important in the life cycle of the virus. The ribozyme's function in nature is to cleave an internal phosphodiester bond and linearize concatemers during rolling circle replication. Crystal structures of the ribozyme have been solved in both pre-cleaved and post-clea...

Using administrative data from the state of Georgia, this paper finds that, on average, across all firms, employing undocumented workers reduces a firm’s hazard of exit by 19 percent. The advantage to firms from employing undocumented workers increases as more firms in the industry do so, decreases with the skill level of the firm’s workers, increases with the breadth of a firm’s market, and in...

OBJECTIVE The objective of this study was to investigate ACE- and chymase-dependent angiotensin I-to-II conversion in human coronary arteries (HCAs). METHODS AND RESULTS HCA rings were mounted in organ baths, and concentration-response curves to angiotensin II, angiotensin I, and the chymase-specific substrate Pro(11)-D-Ala(12)-angiotensin I (PA-angiotensin I) were constructed. All angiotensi...