Correspondence: Farooq A Shiekh URMITE, Faculté de Médecine, 27 Bd Jean Moulin, 13385 Marseille Cedex 5, France Tel +33 4 91 32 44 80 Fax +33 4 91 38 77 72 Email [email protected] Dear editor With great interest, I read a recent article published in the International Journal of Nanomedicine by Guo et al. This study involved an analysis of calcifying nanoparticles to determine the presence of ...

The data on the far-ultraviolet extinction of starlight in our galaxy and in external galaxies is interpreted in terms of the widespread occurrence of organic particles of optical refractive index 1.4 and radii less than or equal to 20 nm. Such particles are candidates for nanobacteria such as recently been found in abundance on the Earth.

The nanotechnology industry is currently in the process of producing new nanoparticles. The biological activity of nanoparticles including adverse as well as beneficial effects tends to increase as their size decreases. The smaller the particles are, the greater their bioactivity and toxicity. Thus, one can easily conjecture the impact ofa nanoparticle if it could also self-replicate. This in v...

OBJECTIVES Randall initially described calcified subepithelial papillary plaques, which he hypothesized as nidi for urinary calculi. The discovery of calcifying nanoparticles (CNP), also referred to as nanobacteria, in calcified soft tissues has raised another hypothesis about their possible involvement in urinary stone formation. This research is the first attempt to investigate the potential ...

background and objective: nanoscopic life forms called nanobacteria or calcifying nanoparticles (cnp) are unconventional agents. these novel organisms are very small (0.1 to 0.5 microns) and possess unusual properties such as high resistance to heat and routine antimicrobial agents. nanobacteria are 100 times smaller than bacteria and protected by a shell of apatite, so they could be as candida...

BACKGROUND AND OBJECTIVE Nanoscopic life forms called Nanobacteria or calcifying nanoparticles (CNP) are unconventional agents. These novel organisms are very small (0.1 to 0.5 microns) and possess unusual properties such as high resistance to heat and routine antimicrobial agents. Nanobacteria are 100 times smaller than bacteria and protected by a shell of apatite, so they could be as candidat...

Biologists typically define living organisms as carbon and water-based cellular forms with “selfreplication” as the fundamental trait of the life process. However, this standard dictionary definition of life does not help scientists to categorize self-replicators like viruses, prions, proteons and artificial life. CNP also named nanobacteria were discovered in early 1990s as about 100 nanometer...

Nanobacteria or living nanovesicles are of great interest to the scientific community because of their dual nature: on the one hand, they appear as primal biosystems originating life; on the other hand, they can cause severe diseases. Their survival as well as their pathogenic potential is apparently linked to a self-synthesized protein-based slime, rich in calcium and phosphate (when available...