Calcifying odontogenic cyst is a rare entity which was first described by Gorlin, and also accounts for 1% of the jaw cysts according to Shear. Due to its diverse histopathology and variable clinical features, there has been a doubt regarding its nature as a cyst or a neoplasm. In this report we present a case of calcifying odontogenic cyst with mural ameloblastomatous presentation in the left ...

Calcifying odontogenic cyst (COC) is an uncommon benign cystic neoplasm of odontogenic origin, which shows extensive diversity in its clinico-pathological appearances and biological behavior. It most commonly occurs in broader age group of 1-82 years in anterior part of jaws which is classically described by presence of ghost cells. There are variants of COC according to clinical, histopatholog...

Calcifying odontogenic cyst (COC) is an odontogenic cyst with accumulation of ghost cells that has central and peripheral subsets. Here, we present an 11-year-old male patient with an intraoral swelling on the left posterior mandibular ridge interfering with eruption of the second molar. Histopathologic examination revealed a cystic lesion lined by ameloblast-like epithelium in the basal layer ...

The calcifying odontogenic cyst (COC), first described by Gorlin et al. in 1962, represents a heterogeneous group of lesions that exhibit a variety of clinicopathologic and behavioral features. COC has been categorized under two basic groups namely, cystic and neoplastic. Even after several classifications and sub-classifications, COC remains an enigma. Very few cases of ameloblastomatous COC h...

background and aims. odontogenic cysts and tumors have a wide spectrum of clinical characteristics that lead to the different management strategies. since definite diagnosis is difficult in some cases, it has been suggested that cd56 may be a candidate marker for definitive diagnosis of some odontogenic tumors. the present study was designed to examine cd56 expression in lesions with histopatho...

AIM To reevaluate all cases previously diagnosed as calcifying odontogenic cyst (COC) from the archives of the Department of Oral Pathology at Mashhad Faculty of Dentistry from 1978 to 2008. MATERIALS AND METHODS Clinical histories and microscopic slides of all cases diagnosed as COC were reviewed and analyzed statistically. The information about patients such as age, sex, clinical features, ...

Background and aims. Odontogenic cysts and tumors have a wide spectrum of clinical characteristics that lead to the different management strategies. Since definite diagnosis is difficult in some cases, it has been suggested that CD56 may be a candidate marker for definitive diagnosis of some odontogenic tumors. The present study was designed to examine CD56 expression in lesions with histopatho...

introduction calcifying odontogenic cyst (coc) is a unique and uncommon odontogenic cyst classified into four groups of cystic, odontoma producing, ameloblastomatous proliferating and neoplastic ones. case presentation a 34-year-old iranian man complaining of a painless facial and palatal swelling of the left side of the maxilla persisted for approximately three years was referred to the depart...

The purpose of this study was to investigate a case of calcifying odontogenic cyst (COC) in which numerous calcifications were observed not only in the lining epithelium, but also in the cyst wall, using cytokeratins 13 (CK13), 19 (CK19), and core binding factor a-1 (cbfa-1) as primary antibodies. Cells of Malassez's epithelial rest were stained as controls. Cells of the epithelial nests in the...

Calcifying cystic odontogenic tumor (CCOT) previously known as calcifying odontogenic cyst (COC) is a relatively rare lesion. It was first reported as a separate pathologic entity by Gorlin et al in 1962 as a likely analog of the cutaneous calcifying epithelioma of Malherbe or pilomatricoma. Because of the diverse clinicohistologic features and the various neoplastic potential, there have been ...