Corticotropin-releasing hormone (CRH) affects cytosolic calcium ion levels. The aim of the present work was to examine the role of protein kinase A (PKA)- and PKC-dependent signalling pathways in mediating the effect of CRH on calcium ion influx (from extra-cellular sources) and calcium ion mobilization (from intra-cellular stores). In this study, we employed a well-known model of neural crest-...

The irreversible thermal inactivation and the thermodynamics of calcium ion binding of Bacillus amyloliquefaciens alpha-amylase in the absence of substrates were studied. The enzyme inactivation on heating was apparently followed by first-order kinetics. The enzyme was stabilized with an increased concentration of calcium ion and thus the inactivation was highly dependent on the state of calciu...

We have evaluated the effects of the following on ion.specific electrode measurement of calcium ion activity in plasma: blood or plasma was stored in various ways for various periods of time, or exposed to air, or small amounts of heparin were added to the blood. Blood may be stored for as long as 120mm at room temperature before calcium ion activitychanges measurably, but plasma stored for 20 ...

CURRY, DONALD L., LESLIE L. BENNETT, AND GEROLD M. GR~DSKY. Requirement for calcium ion in insulin secretiorz by the perfused rut p ancreas. Am. J. Physiol. 214(l): 174-178. 1968.The effect of calcium ion on insulin release was studied in the isolated perfused rat pancreas. Following a standard glucose stimulus, insulin secretion (determined by immunochemical assay of the total portal vein effl...

It was found that ACTH greatly reduced lipogenesis in fat cells in the presence of calcium ion, but not in the absence of calcium ion. Of the enzymes involved in triglyceride synthesis from fatty acid in lipid micelle membranes, only acyl-CoA synthetase was inhibited by calcium ion, the apparent Ki value of calcium ion being 4.2 X 10(-4) M. The Km values of the enzyme for palmitate and ATP were...

Tricalcium silicate cements (TSC) are used in dental traumatology and endodontics for their bioactivity which is mostly attributed to formation of calcium hydroxide during TSC hydration and its subsequent release of calcium and hydroxide ions. The aim of this study was to determine the effect of volume (Vol), exposed surface area (ESA) and pH of surrounding medium on calcium ion release. Three ...

Multivalent batteries, such as magnesium-ion, calcium-ion, and zinc-ion have attracted significant attention next-generation electrochemical energy storage devices to complement conventional lithium-ion batteries (LIBs). Among them, calcium-ion (CIBs) are the least explored due difficult reversible Ca deposition–dissolution. In this work, we examined stability of four different salts with weakl...

introduction: this in vitro study measured and compared ph and phosphate and calcium ions release of a new endodontic material (cem cement), mineral trioxide aggregate (mta), and portland cement (pc) using uv-visible technique, atomic absorption spectrophotometry methods, and ph meter, respectively. materials and methods: each material was placed in a plastic tube (n=10) and immersed in a glass...

The three types of motor axons found in the walking legs of the lobster were shown to respond differently upon exposure to calcium-free solutions. While all fiber types became more excitable initially in calcium-free solutions, only openers became spontaneously active. Fast closers showed the least reduction in rheobase value upon calcium depletion. After 5 minutes in calcium-free solution all ...