Among diverse environmental factors that modify aging, diet has a profound effect. Calorie restriction (CR), which entails reduced calorie consumption without malnutrition, is the only natural regimen shown to extend maximum and mean lifespan, as well as healthspan in a wide range of organisms. Although the knowledge about the biological mechanisms underlying CR is still incipient, various appr...

OBJECTIVE To measure changes in resting metabolic rate (RMR) and body composition in obese subjects following massive weight loss achieved via bariatric surgery or calorie restriction plus vigorous exercise. METHODS Body composition and RMR were measured in 13 pairs of obese subjects retrospectively matched for sex, body mass index, weight, and age who underwent either Roux-en-Y gastric bypas...

The main cause of the development metabolic syndrome seems to be an imbalance calorie intake and energy expenditure. However genetic epigenetic factors, sedentary lifestyle, poor food quality, disturbances in gut microbiota also play a major role. There is no single effective method treatment for syndrome. Dietary therapy increase physical activity along with pharmacological are not fully recom...

Aging is associated with protein damage and imbalance in redox status in a variety of cells and tissues, yet little is known about the extent of age-related oxidative stress in the peripheral nervous system. Previously, we showed a drastic decline in the expression of glial and neuronal proteins in myelinated peripheral nerves with age, which is significantly ameliorated by lifelong calorie res...

Abstract An imbalance between calorie intake and energy expenditure produces obesity. It has been a major problem in societies of the developing developed world. In obesity an excessive amount fat accumulates adipose tissue cells as well other vital organs like liver, muscles, pancreas. The adipocytes contain ob genes express leptin, 16 kDa protein. present communication, we reviewed molecular ...

The following study tried to determine whether Maillard reaction end product-embodied food is significantly more alluring, rewarding, addictive, and cardiovascular taxing than product-free meals. As importantly, does product-containing fare exhibit tolerance measured by increased total calorie consumption per day, progression rising amounts of overweight, withdrawal frequent urges snack dine pr...

Oxidative stress is a state of imbalance free radicals in the cells and one causes various diseases humans. One method that thought to reduce oxidative calorie restriction or fasting. However, its effects remain unclear. This study was conducted determine effect intermittent fasting prolonged on levels malondialdehyde (MDA) as an marker liver plasma New Zealand White rabbits. Fifteen rabbits we...

Overweight and obesity in developing countries is a health problem. An increase body mass index associated with an inflammatory media, hypertension, diabetes mellitus, hypercholesterolemia especially LDL hypertriglycerides thought to be trigger for stroke. Obesity can occur as result of light physical activity due imbalance between energy expenditure calorie intake. The analytic observational r...

OBJECTIVE To evaluate the efficacy and consumer preferences of calorie labeling on menus. DESIGN Between-group experiment. Participants were randomized to view menu items according to 1 of 4 experimental conditions: no calorie information, calorie-only information, calorie plus health statement (HS), and calorie plus the Physical Activity Scale. Participants selected a snack and then rated me...