The milkweed, Calotropis gigantea (L.) W.T. Aiton (Gentianales: Asclepiadaceae) locally known as Akond, is an evergreen, perennial shrub, and is widely distributed in sub-tropical and tropical countries. It has been reported that latices of the milkweeds including C. gigantea contain cardiac glycosides that vary in amount and type between species, between various plant parts of the same species...

The 70% hydroethanolic extracts of Calotropis procera (CP) and Calotropis gigantea (CG) leaves have been evaluated and compared for anti-diarrheal activity using castor oil-induced diarrhea model in rats. Results showed statistically significant reduction in the frequency and severity of diarrhoea produced by castor oil in both CP and CG. The anti-diarrheal effect of CP was found superior to CG...

The latex of Calotropis gigantea is a rich source of useful components that has medicinal properties and one of the main applications is in controlling the heart muscle. The crude latex extract contained many proteins, which are highly basic in nature and exhibited strong dilatation activity. Blood vessel experiment of the latex from Calotropis gigantea was studied in the green frog (Rana hexad...

Natural products and herbal remedies used in traditional folklore medicine have been the source of many medically beneficial drugs because they elicit fewer side effects, relatively cheap, affordable and claimed to be effective. However, in order to make these remedies acceptable to modern medicine, there is a need to scientifically evaluate them to identify the active principles and to underst...

calotropis gigantea (linn) and amoora rohituka (roxb.) have long been used in folkloric medicine for the treatment of various ailments in bangladesh. the present study was designed to investigate the cytotoxicity of isolated compounds from these two plants. two compounds, named β-boswellic acid (compound-1) and 2-methoxy-14-calamenenone (compound-2) were isolated from the flowers of calotropis ...

Ethanolic extract (50 %) of stems of Calotropis gigantea R. Br. (Asclepiadaceae) at doses of 250 and 500 mg kg-1 were studied for hepatoprotective activity in male Wistar rats with liver damage induced using carbon tetrachloride, 2 mL kg-1 twice a week. The protective effect of C. gigantea extract was compared with the standard drug silymarin. Various biochemical parameters such as aspartate am...

A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data. Compounds 1 and 2 displayed inhibitory effects towards chronic myelogenous leukemia K562 and human gastric cancer SGC-7901 cell lines.

Calotropis gigantea is a big shrub; it’s looking like a small tree, sports clusters of waxy flowers that are either white or lavender in colour found. Each flower consists of five pointed petals and a small, elegant "crown" rising from the center, which holds the stamens. This articles is viewed the botanical survey and full details of the plant of calotropis gigantea. It has oval, light green ...

Phytochemical investigations of Calotropis procera leaves have led to the isolation of two new compounds: quercetagetin-6-methyl ether 3-O-beta-D-4C1-galacturonopyranoside (3) and (E)-3-(4-methoxyphenyl-2-O-beta-D-4C1 -glucopyranoside)-methyl propenoate (4), along with eleven known metabolites: nine flavonol and two cinnamic acid derivatives. All metabolites were isolated for the first time fro...

BACKGROUND & OBJECTIVES Identification of novel effective larvicide from natural resources is essential to combat developing resistances, environmental concerns, residue problems and high cost of synthetic insecticides. Results of earlier laboratory findings have shown that Calotropis procera extracts showed larvicidal, ovicidal and refractory properties towards ovipositioning of dengue vectors...