Calotropis procera is a medicinal plant whose pharmacological properties are associated with its latex. Here, the Calotropis procera latex fractions were investigated in an attempt to trace its phytochemical profile and measure its anti-inflammatory and toxicity activity. The crude latex was partitioned, yielding five fractions (49.4% hexane, 5.2% dichloromethane, 2.0% ethyl acetate, 2.1% n-but...

Different parts of Acacia nilotica (L.) Delile, Calotropis procera (Aiton) W.T. Aiton, Adhatoda vasica Nees, Fagoniaar abica L. and Casuarina equisetifolia L. are traditionally used in folk medicine for the treatment of a variety of common ailments like nausea, cold, cough, asthma, fevers, diarrhea, sore throat, swelling, etc. The present study was aimed to evaluate the anti-Helicobacter pylori...

The side effects associated with the usage of synthetic antidiabetic drugs make it imperative to search for alternative drugs from medicinal plants. Therefore, this study was aimed at evaluating the α-amylase and α-glucosidase inhibitory potential of Calotropis procera leaf, as well as its possible mode of inhibiting these enzymes. Acetone, aqueous and ethanolic extracts of C. procera leaf was ...

BACKGROUND AND AIMS Calotropis procera and Calotropis gigantea, originally from warm parts of Africa and Asia, are now pan-tropical and in ecological terms considered an indicator of overgrazed, disturbed lands; they grow successfully in dry areas. Variations in water relations, morphology and photosynthesis of the two species growing in the same habitat were studied to assess possible mechanis...

Phytochemical and biological screening is necessary for the isolation of new compound which lead to the discovery of drug. In the present work the crude MeOH extract and milky latex of Calotropis procera were tested for phytochemical test which indicated the presence of various class of bioactive secondary metabolite such as terpenoids, flavonoids, saponins, steroids and cardiac glycosides. C. ...

The work delt with the growth-inhibitory impact of methanolic extract of Calotropis procera leaves on five pathogenic bacteria, analysed by agar diffusion and broth dilution methods. By agar diffusion method, the extract was found very effective against B. subtilis (MIC= 2.5 mg), while moderate activity was noted against P. mirabilis (MIC= 5 mg). Zone of inhibition was not found for P. aerugino...

BACKGROUND & OBJECTIVES Identification of novel effective larvicide from natural resources is essential to combat developing resistances, environmental concerns, residue problems and high cost of synthetic insecticides. Results of earlier laboratory findings have shown that Calotropis procera extracts showed larvicidal, ovicidal and refractory properties towards ovipositioning of dengue vectors...

In the present investigation various bioassays were conducted to evaluate the anti-termite efficacy of plant latex based formulations to control population of Indian white termite in subtropical soil. Results reveal that crude latex, its fractions and combinatorial fractions have shown very high toxicity against O. obesus. The LD50 values for different latex fractions of 24 h were in a range of...

Medicinal plants have remained the major sources of drugs; in fact many of the Currently available drugs were derived either directly or indirectly from them. The Approach to new drugs through natural products has proved to be the single most successful strategy for the discovery of new drugs. In the past decade, research has been focused on scientific evaluation of traditional drugs of plant o...

Medicinal plants are the local heritage with global importance playing a vital role in world health care system of developing countries. Calotropis procera (Asclepiadaceae), a giant milk weed, is known for its pharmacological importance for centuries. The coarse shrub is a very promising source of anticancerous, ascaricidal, schizonticidal, anti-microbial, anthelmintic, insecticidal, anti-infla...