نتایج جستجو برای: cancer antigen 153
تعداد نتایج: 1089594 فیلتر نتایج به سال:
PSA-TRICOM is a therapeutic vaccine in late stage clinical testing in metastatic castration-resistant prostate cancer (mCRPC). Samarium-153-ethylene diamine tetramethylene phosphonate (Sm-153-EDTMP; Quadramet®), a radiopharmaceutical, binds osteoblastic bone lesions and emits beta particles causing local tumor cell destruction. Preclinically, Sm-153-EDTMP alters tumor cell phenotype facilitatin...
Although microRNAs (miRNA) have been broadly studied in cancer, comparatively less is understood about their role in progression. Here we report that miR-153 has a dual role during progression of colorectal cancer by enhancing cellular invasiveness and platinum-based chemotherapy resistance. miRNA profiling revealed that miR-153 was highly expressed in a cellular model of advanced stage colorec...
The epithelial-mesenchymal transition (EMT) is a crucial step in epithelial cancer invasion and metastasis. The aims of this study were to investigate and validate unidentified micro RNAs (miRNAs) that regulate EMT and to reveal their clinical relevance in epithelial cancer patients. By applying miRNA array screening in a natural epithelial-mesenchymal phenotype cell line pair and in a transfor...
background: cervical cancer is one of the most common types of women’s reproductive cancers. a major risk factor for cervical cancer is exposure to a group of common sexually transmitted viruses called human papillomavirus (hpv). the over expression of hpv 16 i.e., e6 antigen in the tumors of suspected cervical cancer tissues. however e-6 antigen has hyaluronan binding protein site. methods: t...
PURPOSE We tested the hypothesis that serum isoform [-2]proPSA derivatives %p2PSA and Prostate Health Index are accurate predictors of prostate cancer in men scheduled for repeat biopsy. MATERIALS AND METHODS The study was an observational prospective evaluation of a clinical cohort of men with 1 or 2 previous negative prostate biopsies, with persistent suspicion of prostate cancer. They were...
Background and Aim: Lung cancer is the most common cancer among men around the world. The aim of this study was to determine the expression levels of CK19 mRNA marker in the affected patients’ peripheral blood. Materials and Methods: Thirty patients with lung cancer (NSCLC type) were compared with 30 healthy controls. After taking peripheral blood samples and extracting total RNA, cDNA was s...
Background: It is an important clinical means to identify benign and malignant breast diseases caused by nipple discharge through the detection analysis of components in discharge. This study was aimed test expression significance carbohydrate antigen 125 (CA125), 153 (CA153) carcinoembryonic (CEA) cancer patients. 
 Methods: From January 2017 December 2018, 86 patients with invasive ducta...
background: we aimed to value the usefulness of free to total prostate-specific antigen and prostate-specific antigen (psa) density for prostate cancer in the patients with psa levels of 4.0 ng/ml or less. methods: a total of 343 subjects with psa levels of 4.0 ng/ml or less were biopsied. all patients were divided into four groups according to the psa levels: 0 to 1.0 ng/ml, 1.1 to 2.0 ng/ml, ...
سرطان عامل اصلی مرگ در کشورهای توسعه یافته اقتصادی و دومین عامل مرگ در کشورهای در حال توسعه است. سرطان کولورکتال یکی از سومین سرطان رایج و چهارمین دلیل مرگ و میر در جهان است. سرطان کولورکتال در ایران، در مردان، چهارمین سرطان بوده و در زنان دومین سرطان محسوب می¬شود. بیشترین مرگ و میر ناشی از سرطان کولورکتال به علت متاستاز دادن آن است. تشخیص زود هنگام و اتخاذ روش های درمانی مناسب برای این افراد ا...
background: prostate cancer is the most common malignancy among the male population in the united states and the 3rd most common non-skin cancer among men in iran. its prevalence has shown a rising trend in recent decades. the aim of this study was to report the epidemiological features of prostate cancer in patients referred for prostate biopsy in the south of iran and to evaluate the accuracy...
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