The September 1998 issue of EHP contained two articles about the neurotoxicity of carbon disulfide. The "NIEHS News" article (1) reported on a collaborative study that involved scientists from the NIEHS (Nashville, TN). In this study, the neurotoxicity of carbon disulfide was detailed from the earliest molecular alterations to neurobehavioral findings to electrophysiologic and morphologic chang...

IN AN EARLIER STUDY (Barr et al., 1981) we explored the pathogenesis of soft-tissue necrosis induced in guinea-pigs by the concrolled extravascular administration of cytotoxic drugs. This system provides a model of the phenomenon which may complicate the inadvertent perivenous injection of cancer chemotherapeutic agents in clinical practice. The current investigation was undertaken in order to ...

The regioselective ring opening of styrene oxide using elemental iodine and bromine in the presence of disulfides as new catalysts was studied. The conductivity titration and UV spectroscopy were used to study the interaction of iodine with these catalysts. The results indicate that disulfide 11 is efficient in polyiodide formation, and can catalyze this reaction in excellent yield and high reg...

In a prospective cohort study, men of Japanese ancestry were clinically examined from 1965 to 1968. For 7,833 of these men, data on black tea consumption habits were recorded. Since 1965, newly diagnosed cancer incidence cases have been identified: 152 colon, 151 lung, 149 prostate, 136 stomach, 76 rectum, 57 bladder, 30 pancreas, 25 liver, 12 kidney and 163 at other (miscellaneous) sites. Comp...

Carbon disulfide is widely used for the production of viscose rayon, rubber, and other organic materials and it is a feedstock for the synthesis of sulfuric acid. The objective of this paper is to analyze possibilities for efficient production of CS2 from sour natural gas reformation (H2SMR) (2H2S+CH4 =CS2 +4H2) . Also, the effect of H2S to CH4 feed ratio and reaction temperature on carbon disu...

ion from the a-carbon or the b-carbon of a disulfide, followed by b-cleavages yielding C–S or S–S bond scissions. The current mechanistic findings should be generally applicable to other radicaldriven disulfide bond cleavages with different radical species such as the benzyl and methyl pyridyl radicals.