objective: environmental pollution is of major concern today and lead is considered to be one of the most important environmental pollutants. long-term contact with lead causes harmful effects to humans. this study seeks to determine the effects of curcuma longa (turmeric extract) consumption and exercise training on glutathione peroxidase and protein carbonyl in kidney and spleen tissues from ...

A broad range of secondary and tertiary amides has been hydrogenated to the corresponding amines under mild conditions using an in situ catalyst generated by combining [Ru(acac)3], 1,1,1tris(diphenylphosphinomethyl)ethane (Triphos) and Yb(OTf)3. The presence of the metal triflate allows to mitigate reaction conditions compared to previous reports thus improving yields and selectivities in the d...

The ubiquitous ketone carbonyl group generally deactivates substrates toward radical-based fluorinations, especially sites closest to it. Herein, ketones are used instead to direct aliphatic fluorination using Selectfluor, catalytic benzil, and visible light. Selective β- and γ-fluorination are demonstrated on rigid mono-, di-, tri-, and tetracyclic (steroidal) substrates employing both cyclic ...

Low molecular weight gelators that are not easily degraded by enzymes have a range of potential applications. Here, we report new Fmoc-protected dipeptides in which the amide carbonyl group has been replaced by an oxetane ring. Remarkably one of these peptidomimetics, but not the corresponding dipeptide, is an effective gelator, forming hydrogels at a concentration of 3 mg mL-1. On assembly, th...

Trinuclear cyclopentadienylniobium carbonyls are of interest since Cp3Nb3(CO)7 (Cp=eta5-C5H5) is a stable molecule having a unique face-bridging carbonyl group formally donating six electrons to the Nb3 triangle through one Nb-C sigma-bond and two orthogonal pi-bonds. In this connection, the molecules Cp3Nb3(CO)n (n=9, 8, 7, 6) have been examined by density functional theory. The saturated deri...