OBJECTIVES To compare the potential for postoperative laparoscopic adhesion formation utilizing either monopolar cautery or ultrasonic energy and to determine whether there is added benefit with the addition of a suspension of hyaluronate/carboxymethylcellulose in saline versus saline alone. METHODS Injuries were induced in rabbits by using monopolar cautery on 1 uterine horn and adjacent si...

Dissolving microneedles are especially attractive for transdermal drug delivery as they are associated with improved patient compliance and safety. Furthermore, microneedles made of sugars offer the added benefit of biomolecule stabilisation making them ideal candidates for delivering biological agents such as proteins, peptides and nucleic acids. In this study, we performed experimental and fi...

BACKGROUND Among the chronic leg ulcers, venous ulcers are the most common and constitute a major burden to public health. Despite all technology available, some patients do not respond to established treatments. In our study, carboxymethylcellulose was tested in the treatment of refractory chronic venous ulcers. OBJECTIVE To evaluate the efficacy of carboxymethylcellulose 20% on the healing ...

The current study was designed to investigate the efficacy of a hyaluronate/carboxymethylcellulose membrane for the prevention of post-operative adhesion in a rat uterine horn model. This is a prospective double-blinded controlled study. Nineteen injured uterine horns were treated with a hyaluronate/carboxymethylcellulose membrane as a barrier and 19 injured uterine horns without any treatment ...

Oral mucosa is an attractive region for the local and systemic application of many drugs. Oral mucoadhesive films are preferred for their prolonged time of residence, the improved bioavailability of the drug they contain, their painless application, their protection against lesions, and their nonirritating properties. This work was focused on preparation of nonmedicated carmellose-based films u...

The most widely-used wall materials for spray-dried microencapsulation have limitations in cost-effectiveness, health benefits and sustainability. Wood hemicelluloses, by-products of the forestry industry, including galactoglucomannans glucuronoxylans potential to be utilized as innovative materials. This study investigated applicability galactoglucomannan glucuronoxylan their mixtures with car...

introduction: idiopathic pulmonary fibrosis (ipf) is a relentlessly progressive and usually fatal lung disease of unknown etiology for which no effective treatments currently exist. in the adults type i and ii pneumocytes, forms components of the alveolar epithelial cells. in this study, we investigated the effect of thalidomide on the alveolar epithelial cells (type i and ii pneumocytes) in th...

Infections that occur after the insertion of biomedical devices are a major problem; potential sources infection due to adhesion bacteria on surface implants, form biofilms. In order combat or effectively prevent various microbial, which in medical procedures, we try make compounds and materials formation development microbial biofilm. The aim this study was obtain nanostructured surfaces based...