Context Carcinoembryonic antigen analysis of pancreatic cyst fluid is the tumor marker of choice for preoperatively differentiating mucinous from non-mucinous cystic lesions. Objective We aim to determine the most accurate cyst carcinoembryonic antigen cut-off value for distinguishing mucinous cysts from non-mucinous cysts with a focus on discriminating intraductal papillary mucinous neoplasms....

OBJECTIVE We conducted a prospective study of 103 consecutive patients with non-small cell lung cancer who underwent a curative lobectomy to test whether circulating tumor cells detected in the peripheral blood by means of reverse transcriptase-polymerase chain reaction of carcinoembryonic antigen messenger RNA is a prognostic indicator independent of tumor stage in patients with non-small cell...

Measurement of plasma levels of carcinoembryonic antigen, though not infrequently helpful in the mangement of patients with colorectal cancer, has serious limitations in terms of specificity and sensitivity. Many benign conditions may cause elevations of carcinoembryonic antigen, and even far advanced metastatic large bowel cancer may be associated with normal levels. Major treatment decisions ...

Native human carcinoembryonic antigen is rapidly removed from the circulation by the rat liver Kupffer cell after intravenous injection. The molecule is subsequently transferred to the hepatocyte in an immunologically identifiable form. Carcinoembryonic antigen has a circulatory half-life of 3.7 (+/- 0.8) min, and cellular entry is by receptor-mediated endocytosis. Non-specific fluid pinocytosi...

BACKGROUND Using carcinoembryonic antigen in discriminating between benign and malignant disease remains controversial. AIMS We aim to evaluate the diagnostic accuracy of cyst fluid carcinoembryonic antigen in predicting malignant pancreatic cystic lesions. METHODS We performed a literature search of MEDLINE and EMBASE. We included studies that compared the diagnostic accuracy of carcinoemb...

CONTEXT Colonoscopy is essential for synchronous and metachronous cancer detection. Carcinoembryonic antigen is a colorectal cancer tumor marker, important as a follow-up tool in patients with previous colorectal cancer. False-positive carcinoembryonic antigen elevation results in multiples exams and in patient anxiety. In literature, there is reference to transient carcinoembryonic antigen inc...

Objective The sensitivity of pancreatic juice cytology for intraductal papillary mucinous neoplasm is insufficient. We evaluated the usefulness of repeated pancreatic juice cytology via an endoscopic naso-pancreatic drainage tube combined with carcinoembryonic antigen level of pancreatic juice for the diagnosis of malignant intraductal papillary mucinous neoplasm. Methods Between April 2004 and...