نتایج جستجو برای: cardiac conduction system disease
تعداد نتایج: 3736785 فیلتر نتایج به سال:
Rationale: Nkx2.5 is one of the most widely studied cardiac-specific transcription factors, conserved from flies to man, with multiple essential roles in both the developing and adult heart. Specific dominant mutations in NKX2.5 have been identified in adult congenital heart disease patients presenting with conduction system anomalies and recent genome-wide association studies implicate the NKX...
Two patients with dystrophia myotonica showed high-grade atrio-ventricular block. Both underwent electrophysiological studies which revealed sinus and A-V nodal disease with normal intraventricular conduction in 1 case and His-Purkinje conduction disease in the other. Dystrophia myotonica may, therfore, involve all parts of the cardiac conduction system and may affect the generation of cardiac ...
the coronary slow flow phenomenon (csfp) is characterized by a delayed coronary blood flow in the absence of an obstructive coronary artery disease. although the relation between the csfp and myocardial ischemia has been reported previously, there is no knowledge about the relationship between the csfp and the conduction system disorder. in this case report, we describe a patient with the csfp ...
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism. Defects in this specialized wiring system can lead to syncope and sudden cardiac death. Thus, a greater understanding of cardiac conduction development may help to prevent these dev...
Myotonic dystrophy (DM) is the most common form of muscular dystrophy and is caused by expansion of a CTG trinucleotide repeat on human chromosome 19. Patients with DM develop atrioventricular conduction disturbances, the principal cardiac manifestation of this disease. The etiology of the pathophysiological changes observed in DM has yet to be resolved. Haploinsufficiency of myotonic dystrophy...
background: cardiac involvement in systemic sclerosis (ssc) is more prevalent than previously thought. in this study, the frequency and severity of cardiovascular involvement were assessed in ssc patients referred to firouzgar hospital. methods: fifty-eight patients with ssc, selected from the data bank of ssc patients, were reviewed for the frequency and severity of 8 organ involvements in thi...
BACKGROUND PRKAG2 mutations cause glycogen-storage cardiomyopathy, ventricular preexcitation, and conduction system degeneration. A genetic approach that utilizes a binary inducible transgenic system was used to investigate the disease mechanism and to assess preventability and reversibility of disease features in a mouse model of glycogen-storage cardiomyopathy. METHODS AND RESULTS Transgeni...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید