OBJECTIVE Coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) is associated with a systemic inflammatory response. This is mainly attributed to cytokine release caused by CPB and global myocardial ischemia. Coronary artery bypass grafting without cardiopulmonary bypass (off-pump CABG, OPCAB) is now accepted as a less invasive technique than conventional CABG. This study was...

UNLABELLED Cardiopulmonary bypass (CPB) induces a systemic inflammatory response characterized by release of proinflammatory cytokines, including interleukin 6 (IL-6). Recent reports suggest that plasma IL-6 is increased after CPB. Previous studies evaluating the influence of duration of CPB and/or aortic cross-clamp time on the release of IL-6 are conflicting. Infusion of blood and blood produ...

background: accidents are the second reason for mortality and morbidity in iran. among them, brain injuries are the most important damage. clarification of the effects of brain injuries on different body systems will help physicians to prioritize their treatment strategies. in this study, the effect of pure brain trauma on the cardiovascular system and lungs 24 hours post trauma was assessed. m...

INTRODUCTION Cardiopulmonary bypass causes a series of inflammatory events that have adverse effects on the outcome. The release of cytokines, including interleukins, plays a key role in the pathophysiology of the process. Simultaneously, cessation of ventilation and pulmonary blood flow contribute to ischaemia-reperfusion injury in the lungs when reperfusion is maintained. Collapse of the lung...

conclusions no significant difference in reducing post bypass inflammation between preoperative steroid treatment and combined preoperative and intraoperative steroid administration reported and they had the same effects. results in both groups, no significant difference with variation of expression for il-6 (inflammatory factor) and il-10 (anti-inflammatory factor) in different times after byp...

OBJECTIVE Neonatal cardiac surgery with cardiopulmonary bypass is often complicated by morbidity associated with inflammation and low cardiac output syndrome. Hydrocortisone "stress dosing" is reported to provide hemodynamic benefits in some patients with refractory shock. Development of cardiopulmonary bypass-induced adrenal insufficiency may provide further rationale for postoperative hydroco...

there is a paucity of literature regarding iatrogenic aortic valve perforation after cardiac operation is performed in the vicinity of the aortic valve. this report describes the clinical, echocardiographic, and angiocardiographic recognition of iatrogenic aortic valve perforation in a patient who had previously under gone membranous ventricular septal defect and pulmonary stenosis. five days a...

a 47 year-old female died after mitral valve replacement. post-cardiopulmonary bypass right ventricle was not able to pump despite good left ventricular contractility. at microscopic examination, diffuse right ventricular fatty infiltration was found. we found no previous report of this pathology in patients with mitral stenosis