BACKGROUND It has been suggested that host matrix metalloproteinase-2 (MMP-2) present in dentin may be involved in caries progression, however, its response to caries is not known. Bone sialoprotein (BSP) has been implicated in dentin mineralization and MMP-2 modulation. OBJECTIVE To identify and compare the distribution of MMP-2 and BSP in healthy human coronal dentin and those with early ca...

The effects of dietary sucrose and systemic glucocorticoid treatment on the response of the pulpodentinal complex to dental caries were examined in an experimental rat model. The possible role of dentinal caries on dentin formation was also examined. After 5-6 weeks of a dietary and/or medication period, the areas of dentin formation and dentinal caries were quantified in the molars of growing ...

abstract statement of problem: there is no enough published data about the shear bond strength of resin modified glass ionomer adhesives on caries-affected primary tooth dentin excavated using minimally invasive systems. objectives: to evaluate the shear bond strength of 2 different adhesives (one resin modified glass ionomer and one resin) using two caries removal techniques on healthy and car...

ARTICLE INFO Abstract Article History: Received 2 August 2015 Accepted 2 November 2015 Statement of Problem: There is no enough published data about the shear bond strength of resin modified glass ionomer adhesives on caries-affected primary tooth dentin excavated using minimally invasive systems. Objectives: To evaluate the shear bond strength of 2 different adhesives (one resin modified glass...

The aim of this study was to evaluate the effect of 2% chlorhexidine digluconate (CHX) on immediate bond strength of etch-and-rinse adhesive to sound (SD) and caries-affected (CAD) primary dentin compared with permanent dentin. Flat dentin surfaces from 20 primary molars (Pri) and 20 permanent molars (Perm) were assigned to 8 experimental groups (n=5) according to tooth type (Pri or Perm), dent...

This study evaluated the effect of sterilization method on the bond strength of caries-affected dentin before artificial caries development and after restoration. Twelve bovine incisors were sectioned perpendicularly to their long axes at 7 mm from the amelodentinal junction. They were painted with acid-resistant nail varnish, except on an exposed coronal dentin area. Four groups were formed (n...

AIM The aim of this study was to evaluate the carious dentin removal efficacy of new rotary polyamide burs capable of selectively removing infected dentin without removing sound dentin. METHODS AND MATERIALS This study included 40 subjects with bilateral occlusal carious lesions on mandibular first permanent molars. The lesions were randomly assigned to receive one restoration after carious d...

Dentin can be described as a biological composite with collagen matrix embedded with nanosized hydroxyapatite mineral crystallites. Matrix metalloproteinases (MMPs) and cysteine cathepsins are families of endopeptidases. Enzymes of both families are present in dentin and collectively capable of degrading virtually all extracellular matrix components. This review describes these enzymes and thei...

objective: the aim of this study was to evaluate the microtensile bond strength to sound and caries-affected dentin using single bond and adper prompt-l-pop adhesives. materials and methods: sixteen extracted human molars with carious lesions extended halfway through dentin were ground to expose the caries affected and the surrounding normal dentin. the samples were divided into two groups of e...