We conducted a parallel group randomized controlled trial of children initially aged 2 to 3 y who were caries free, to prevent the children becoming caries active over the subsequent 36 mo. The setting was 22 dental practices in Northern Ireland, and children were randomly assigned by a clinical trials unit (CTU) (using computer-generated random numbers, with allocation concealed from the denta...

background:   to find out if there is an association between levels of salivary mutans streptococci (ms)   materials and methods:   t -test were used to find differences between groups. p   results:   p   p   p   conclusion:   present study showed a strong association between maternal and child salivary   ms levels indicating that mother’s ms count could be an important risk indicator for ecc d...

This randomized parallel group clinical trial assessed whether combined antibacterial and fluoride therapy benefits the balance between caries pathological and protective factors. Eligible, enrolled adults (n = 231), with 1-7 baseline cavitated teeth, attending a dental school clinic were randomly assigned to a control or intervention group. Salivary mutans streptococci (MS), lactobacilli (LB),...

Environmental influences on the development and progression of dental caries are well known; however, there is little evidence of a genetic component imparting susceptibility to dental caries. The aim of this study was to investigate the relationship between a single nucleotide polymorphism in the vitamin D receptor TaqI locus and dental caries susceptibility in a Chinese population. This case-...

Amino acid pattern in total saliva was studied in 43 children with caries, aged 12-15 years, using the method of ion exchange chromatography. The results were compared to those obtained in a control group of 39 children without caries. In saliva from the children with caries, a significantly lower level of arginine (22.02 mumol/l), and a complete lack of histidine and its derivatives were obser...

The objective of this study was to measure the effectiveness of fluoride varnish as a public health intervention to prevent caries on partially erupted first and second permanent molars among 6-11 year old children at high risk for caries. In a six-month clinical trial, 105 children were randomly divided into a fluoride varnish (Duraphat) group (117 molars) or a control group (117 molars). The ...

background: an anti-cariogenic diet containing probiotics can be effective in caries prevention. this animal study compared the effects of milk and yogurt on streptococcus sobrinus counts and caries score. materials and methods: a total of 36 male rats were infected with s. sobrinus (27,607) and divided into three groups. group a and b received 200 ml of milk and 100 g of yogurt per day, respec...

AIM To evaluate the caries prevalence and related variables in Type 1 diabetic and non-diabetic children and among the diabetic children according to their metabolic status. METHODS Sixty-eight diabetic and 136 non-diabetic children, matching by gender and age (4-14 years) were enrolled. The diabetic children were divided: a) 20 children in good metabolic control (Hb1ac≤7.5) and b) 48 childre...

The purpose of this article is to describe the Rampant Caries Control Program established in the operative dentistry third-year clinic at the University of Iowa College of Dentistry. This program represents a new approach to the management of high caries risk and high caries activity patients who come to the school. The patients are referred initially to the third-year operative clinic only for...