Carbapenem resistance due to acquired metallo-beta-lactamases (MBLs) is considered to be more serious than other resistance mechanisms. The aim of this study was to evaluate the antibacterial activity of Zataria multiflora Boiss and Carum copticum plants on IMP-producing P.aeruginosa strains. This experimental study was carried out on hospitalized burn patients during 2011 and 2012. Antibiotics...

Effect of Colchicine on Polyploidy Induction and Morphophysiological Characteristics Ajowan (Carum copticum L.) Population Sistan Geographical Area

Background and Aims: Because of the toxicity and side-effects of synthetic drugs, there is a growing interest in biomedical plants. The aim of this study was to evaluate in vitro antileishmanial activity of Carum copticum essential oil against Leishmania (L) major. Materials and Methods: Nineteen experimental groups were designed to determine the effect of Carum copticum essential oil against ...

The effect of exogenous application of nano-iron chelate (100 and 200 mg/l) in early flowering stage on components of essential oils (EOs) of Carum copticum was evaluated. The EO extracted by hydrodistillation from Iranian C. copticum was characterized by means of GC/MS. The nano-iron chelate application increased γterpinene and thymol and decreased α-pinene, β-pinene and p-cymene concentration...

Carum copticum L. commonly known as "Ajwain" is cultivated in many regions of the world including Iran and India, states of Gujarat and Rajasthan. Traditionally, C. copticum has been used in the past for various therapeutic effects including bloating, fatigue, diarrhea, abdominal tumors, abdominal pain, respiratory distress, and loss of appetite. It has other health benefits such as antifungal,...

Carum copticum from Apiaceae family has several biological effects including analgesic, anti-inflammatory, anxiolytic and antispasmodic activities. This study was designed to evaluate its effect on suppression of naloxone-induced morphine withdrawal signs. Hydroalcoholic and polyphenolic extracts were prepared according to the standard methods. Male mice (25-30 g) were made dependent by subcuta...

medicinal plant powders have traditionally been used as grain protectants against stored-product insect pests. in this study, insecticidal activity of carum copticum l. and cuminum cyminum l. powders was assessed on adults of sitophilus granarius l. and tribolium confusum jacquelin du val. experiments were carried out on wheat at 27 ± 1 ºcand 55 ± 5% r. h. the mortality increased with increasin...

Emergence of drug-resistant strains has demanded for alternative means of combating fungal infections. Oils of Carum copticum and Thymus vulgaris have long been used in ethnomedicine for ailments of various fungal infections. Since their activity has not been reported in particular against drug-resistant fungi, this study was aimed to evaluate the effects of oils of C. copticum and T. vulgaris ...

BACKGROUND Quorum sensing is a microbial cell-to-cell communication process. Quorum sensing bacteria produce and release extracellular messenger molecules called autoinducers. Gram-positive and Gram-negative, homoserine lactones, and oligopeptides are autoinducers used to communicate and regulate gene expression. OBJECTIVES The goal of this study was to assess the impact of subinhibitory conc...