To test the hypothesis that under restricted and surfeit protein intake the mammary gland undergoes adaptive regulation, changes in mammary tissue mRNA abundance of cationic amino acid (AA) transporter (CAT)-1, CAT-2B, alanine/serine/cysteine/threonine transporter 1 (ASCT1), and broad specificity transporter for neutral and cationic AA (ATB(0,+)), and CAT-1 protein abundance were investigated a...

A cat kidney cell line, CRFK-F2, was successfully inoculated in suspension and in monolayer culture with a purified mouse mammary tumor virus derived from RIII milk. The virus produced by the infected cells was identified by immunogluorescence, electron microscopy, and RNA-directed DNA polymerase assays; it was a B-type virion that did not cross-react with mouse or feline leukemia-sarcoma virus...

this study is a case report of bilateral perivascular chorioretinal lesions associated with bartonella henselae. a 37-year-old woman presented with headache and blurred vision in both eyes aggravating occasionally during five years. she was otherwise healthy, with best-corrected visual acuities were 20/20 in both eyes. history of close contact with cats was more than merely eye-catching upon ex...

BACKGROUND Molecular marker based cancer diagnosis gaining more attention in the current genomics era. So, Hspb1 and Tp53 gene characterization and their mRNA expression might be helpful in diagnosis and prognosis of cat mammary adenocarcinoma. It will also add information in comparative cancer genetics and genomics. OBJECTIVES Eight tumors of Siamese cats were analyzed to ascertain germ-line...

models have been crucial to increase knowledge about oncogenic mechanisms but due to the limitations of rodents and cell culture approaches, they are viewed as artificial models, whereas the spontaneous tumors in pets are empirically considered to be a more powerful and reliable tool. With the publication and full annotation of cat's genome [1], researchers showed that the genome of the cat was...

although most breast cancers are adenocarcinomas of the mammary gland, primary breast sarcomas may also arise from mammary gland mesenchymal tissue. sarcomas represent less than 1% of primary breast neoplasms. these tumors are at high risk of recurrence and are known to have poor prognosis. surgical resection is the primary treatment for these lesions and axillary lymph node dissection is not r...

  Although most breast cancers are adenocarcinomas of the mammary gland, primary breast sarcomas may also arise from mammary gland mesenchymal tissue. Sarcomas represent less than 1% of primary breast neoplasms. These tumors are at high risk of recurrence and are known to have poor prognosis. Surgical resection is the primary treatment for these lesions and axillary lymph node dissection is no...