نتایج جستجو برای: cd42
تعداد نتایج: 57 فیلتر نتایج به سال:
background: the purpose of the present in vitro study was to evaluate the effect of long term storage of conventional platelet concentrates (pcs) on major platelet receptors cd42b and cd41/cd61 by flow cytometry method and also measuring the overall platelet procoagulant activity status using platelet factor 3 (pf3) assay. materials and methods: six random units of conventional platelet concent...
I t is widely believed that cardiovascular risk factors promote atherogenesis by damaging endothelium. Endothelial status has been mainly assessed by focusing the attention on the quantification of the endothelium capacity to modulate arterial vasomotion. An alternative way to get information on endothelial health is to measure products of endothelial cell injury. Quantification of circulating ...
The thrombocytopenia and absent radii (TAR) syndrome is a rare disease associating bilateral radial agenesis and congenital thrombocytopenia. Here, we investigated in vitro megakaryocyte (MK) differentiation and expression of c-mpl in 6 patients. Using blood or marrow CD34(+) cells, the colony-forming unit (CFU)-MK number was markedly reduced. CD34(+) cells were also cultured in liquid medium i...
Dielectronic recombination (DR) and radiative recombination (RR) data for carbon-like ions forming nitrogen-like ions have been calculated as part of the assembly of a level-resolved DR and RR database necessary for modelling of dynamic finite-density plasmas (Badnell et al. 2003). Total DR and RR rate coefficients are presented and the results discussed for N to Zn24+, as well as Kr30+, Mo36+,...
ETS2 and ERG are transcription factors, encoded on human chromosome 21 (Hsa21), that have been implicated in human cancer. People with Down syndrome (DS), who are trisomic for Hsa21, are predisposed to acute megakaryoblastic leukemia (AMKL). DS-AMKL blasts harbor a mutation in GATA1, which leads to loss of full-length protein but expression of the GATA-1s isoform. To assess the consequences of ...
The effects of Notch signaling on human megakaryocytic and erythroid differentiation were investigated by exposing human CD34(+) progenitor cells to an immobilized chimeric form of the Notch ligand, Delta-like4 (Dll4Fc). Exposure of human cord blood CD34(+) cells to Dll4Fc induced a modest enhancement of erythroid cell production. Conversely, under megakaryocytic culture conditions, Dll4Fc stro...
The effects of Notch signaling on human megakaryocytic and erythroid differentiation were investigated by exposing human CD34 progenitor cells to an immobilized chimeric form of the Notch ligand, Delta-like4 (Dll4Fc). Exposure of human cord blood CD34 cells to Dll4Fc induced a modest enhancement of erythroid cell production. Conversely, under megakaryocytic culture conditions, Dll4Fc strongly i...
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