The global prevalence of celiac disease is of one person per 250 inhabitants. The disease is induced by gluten, a peptide contained in wheat, rye and barley that during small intestinal digestion generates smaller peptides. Some of these are resistant to hydrolysis and cross through the epithelium into the mucosa, inducing a cascade of immune reactions leading to the appearance of the disease i...

Non-celiac gluten sensitivity has recently been recognized by the scientific community as a part of gluten-related disorders, and is defined as a condition with gastrointestinal and/or extra-intestinal symptoms triggered by gluten ingestion in the absence of celiac disease and wheat allergy. Currently, there is no specific serological marker and non-celiac gluten sensitivity remains a diagnosis...

celiac disease is a chronic, systemic and autoimmune disorder of gastrointestinal track that involves approximately 1% of individuals of all ages throughout the world. the collaboration of environmental factor such as gluten proteins and genetic factors, notably hla-dq2 and/or hla-dq8 trigger the disease. gluten-free diet is the simply and merely safe and proficient existing treatment. this art...

OBJECTIVE Celiac disease is an intestinal disorder identified by mucus inflammation, villous atrophy and crypt hyperplasia. This disorder can be controlled by elimination of gluten from daily diet. Patients with celiac disease are at greater risk of gastrointestinal malignancy and non-Hodgkin lymphoma than are the general population. This study tries to present the value of gluten patch test fo...

Background Celiac disease (CD) is a systemic autoimmune disorder due to immune response triggered by ingestion of gluten in the diet. Treatment with lifelong gluten-free diet may impact negatively on the health-related quality of life and may lead to psychological disturbances. The purpose of study was to evaluate quality of life, depression and anxiety in children with celiac disease. Material...

background: the most common neurologic manifestation of gluten sensitivity is ataxia, which accounts for up to 40% of idiopathic sporadic ataxia. timing of diagnosis of gluten ataxia is vital as it is one of the very few treatable causes of sporadic ataxia and causes irreversible loss of purkinje cells. antigliadin antibody (aga) of the igg type is the best marker for neurological manifestation...

gluten associated disorders and the question around these associations has recently attracted attentions of many health professionals. this is because of high prevalence of undiagnosed gluten related disorders presenting with a multitude of symptoms and complications inside and outside small bowel. while the environmental factors associated with a complex genetics are leading to destructions of...

background : â  celiac disease (cd) is an immune-mediated inflammation of the small intestine caused by sensitivity to dietary gluten and related proteins in genetically sensitive individuals . recurrent aphthous stomatitis (ras) is an inflammatory condition characterized by painful recurrent, single or multiple ulcerations of the oral mucosa. the association between cd and ras has been evaluat...

1. the most important challenge in diagnosis of celiac disease is not-performing the diagnostic tests in suspected persons. because of multi-organ damage and multiple manifestations of disease, diagnosis of celiac disease may be delayed. it seems general physicians should be aware about uncommon presentations of disease and indications of celiac tests. 2. the second most important challenge is ...

Many recent studies overshadow the effects of gluten-free diet. Gluten-free diet positive effects were observed in celiac disease patients: increase in body mass index, higher energy intakes, reducing adiposity gain, moderates the risk of the associated complications. However, adhering to a gluten-free diet is difficult for many people. A new solution is needed for quality of life of celiac dis...