The cultivation of oleaginous yeasts on various agro-industrial residues and the subsequent production microbial lipids (single-cell oils), which can be used as starting materials for synthesis both “second generation” biodiesel types oleochemicals, is considered one most important approaches Industrial Biotechnology, in terms circular economy green sustainable development. In this study, seven...

Abstract Cellular transformation leading to cancer development involves multiple changes in the cellular pool of nutrients and macromolecules, including lipids. Tumors switch de novo lipid pathway preferentially accumulate some lipids while excluding others, such as omega-3 (n-3) fatty acids bioactive derived from them, tumor microenvironment. These lipids, known specialized pro-resolving (SPM)...

Among all the biomolecules that form corona of nanomaterials, lipids are somehow less studied and characterized. In present paper, we report on first investigation lipid content biomolecular formed around few layers graphene (FLG) oxide (GO) nanomaterials. Our work revealed significantly different signatures associated with each two materials biocorona in human plasma FLG GO is enriched or depl...

Lipid replacement therapy (LRT) has been used along with other strategies, such as antioxidant therapy, to replace damaged or oxidized cellular lipids that accumulate during aging and in various clinical conditions. Differing from traditional lipid nutritional supplementation, LTR replacement lipids are protected from oxidation and damage during storage, ingestion and digestion. Important lipid...

Neurodegenerative lysosomal storage disorders (LSDs) are severe and untreatable, and mechanisms underlying cellular dysfunction are poorly understood. We found that toxic lipids relevant to three different LSDs disrupt multiple lysosomal and other cellular functions. Unbiased drug discovery revealed several structurally distinct protective compounds, approved for other uses, that prevent lysoso...