peripheral (autonomic and somatic) nervous systems. In the autonomic (sympathetic and parasympathetic) nervous system, acetylcholine is released from all preganglionic neurons, as well as from postganglionic parasympathetic neurons. Degradation of acetylcholine by the enzyme acetylcholinesterase occurs in the synapse between the presynaptic and postsynaptic membranes. There are two types of pos...

Trihexyphenidyl or Artane® /Parkinane® is an anti-cholinergic drug belonging to the antimuscarinic class. It used in treatment of Parkinson’s disease and widely psychiatry for management extrapyramidal side effects neuroleptics. Its overdose leads a central peripheral anticholinergic syndrome. We report here case seven-year-old Senegalese boy who developed signs intoxication due accidental inge...

We report two cases of unintentional poisoning with anticholinergic agents. The first patient, a 7-year-old girl, was prescribed four different medications by a general practitioner for treatment of abdominal colic and diarrhoea. All drugs had anticholinergic properties. The second patient, a 16-month-old boy, ingested his mother's cyproheptadine tablets. Both children presented with central an...

Rabbit syndrome is described as a late onset extrapyramidal side effect of antipsychotic therapy. In the present case rabbit syndrome is described in a young adult as an acute complication of treatment with haloperidol which showed a favourable response to the anticholinergic treatment. Key Words: Rabit Syndrome, antipsychotics,anticholinergic agent.

Background: This meta-analysis aimed to evaluate the efficacy and safety of tibial nerve stimulation (TNS) anticholinergic drugs (ACDs) for treatment overactive bladder syndrome (OAB).