Posttraumatic cerebral infarction is a rare complication and is an indicator of poor clinical outcome of head-trauma in spite of appropriate medical and surgical interventions. Cerebellar infarction following head trauma is also very rare and only a few reported cases are available in literatures. A 2-year-old child sustained head injury in a car accident and underwent surgery because of cerebr...

posttraumatic cerebral infarction is a rare complication and is an indicator of poor clinical outcome of head-trauma in spite of appropriate medical and surgical interventions. cerebellar infarction following head trauma is also very rare and only a few reported cases are available in literatures. a 2-year-old child sustained head injury in a car accident and underwent surgery because of cerebr...

Background: Central renin angiotensin system has an important role on the cerebral microcirculation and metabolism. Our previous work showed that inhibition of angiotensin converting enzyme (ACE) activity prior to induction of ischemia protected the brain from severe ischemia/reperfusion (I/R) injuries. This study evaluated the impacts of post-ischemic inhibition of ACE, enalapril, on brain inf...

background: nitric oxide synthase (nos) activity is increased during hypertension and cerebral ischemia. nos inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (bbb) disruption and cerebral edema formation during stroke in acute hypertension. here, we investigated the role of nos inhibition in progression of edema formation and bbb d...

Background: Nitric oxide synthase (NOS) activity is increased during hypertension and cerebral ischemia. NOS inactivation reduces stroke-induced cerebral injuries, but little is known about its role in blood-brain barrier (BBB) disruption and cerebral edema formation during stroke in acute hypertension. Here, we investigated the role of NOS inhibition in progression of edema formation and BBB d...

background: in patients with acute ischemic cerebral infarction, thrombolytic therapy using intravenous tissue plasminogen activator (iv?tpa) necessitates precise documentation of symptoms’ onset. the aim of this study was to identify major barriers related to the iv?tpa injection in such patients. materials and methods: between 2014 and 2015, patients with definitive diagnosis of acute cerebra...

infection-related cerebral venous sinus thrombosis (cvst) is a rare cerebral vascular diseases which has no pathognomonic sign or definite diagnostic approach. it is crucial to early suspect and recognize the disease to lower morbidity and mortality of it. however, its low incidence and atypic presentation often leads to misdiagnosis and treatment delay which increase complications and mortalit...

background susceptibility-weighted imaging (swi) is extremely sensitive in the detection of superparamagnetic iron oxide (spio) nanoparticle-labeled cells. however, no study has compared molecular imaging for stem cell detection using swi and other mri pulse sequences. objectives this study aims to assess the sensitivity of swi in detecting spio nanoparticle-labeled, human bone marrow-derived m...

We report an uncommon case of simultaneous cardio-cerebral infarction, due to Inferior – right ventricle ST Segment Elevation Myocardial Infarction (STEMI) with acute ischemic stroke. Incidence cardio cerebral infarction is exceptionally rare, incidence rate as low 0.009%. Hemodynamic compromise in patients myocardial may result the blood flow reduction that cause hemodynamic Due rarity this co...

Background: Angiotensin II (Ang II) has an important role on cerebral microcirculation however, its direct roles in terms of ischemic brain edema need to be clarified. This study evaluated the role of central Ang II by using candesartan, as an AT1 receptor blocker, in the brain edema formation and blood-brain barrier (BBB) disruption caused by ischemia/reperfusion (I/R) injuries in rat. Methods...