Cerebrospinal fluids were treated with acid and the extent of protein denaturation along with surface perturbations was followed spectrophotometrically (method of difference spectra). It was found that the fluid samples from patients suffering from a number of neurologic diseases differed considerably among themselves and from pure proteins. The spectrophotometric differences obtained by the ad...

A possibility to use the Membrane-Introduction Mass Spectrometry (MIMS) with membrane separator interface has evolved into a powerful method for measurement of anaesthetic agents absolute concentration in blood plasma and cerebrospinal fluid for the study of blood-brain barrier (BBB) properties. Recent advanced a new membrane material was used for drug concentration measurement in biologic flui...

mumps infection is endemic in iran. our objective was to evaluate the presence of anti mumps antibodies ( igm & igg) in cerebrospinal fluid in mumps meningoencephalitic children. a prospective/cross-sectional study was performed in tehran, iran (2003 to 2004) and serum anti mumps antibodies (igm) were detected (quantitive; elisa) in meningoencephaltis patients. specific anti mumps antibodies (i...

the use of flow cytometry in the clinical laboratory has grown substantially in the past decade. flow cytometric analysis provides a rapid qualitative and quantitative description of multiple characteristics of individual cells. for example, it is possible to detect the cell size and granularity, aspects of dna and rna content and the presence of cell surface and nuclear markers which are used ...

The effect of ammonium chloride (systemic acidosis) and probenecid on the distribution of DMO in intraocular and cerebrospinal fluids has been studied. These drugs increased the level of DMO in intraocular fluids so that DMO was found in excess of plasma levels at plasma levels which normally result in a deficit of DMO in intraocular fluids. Their action seemed to be explained in part by a bloc...

1. During pathological states of iron-overload or oxidant stress, low-molecular-mass iron can become available within extracellular fluids. 2. This iron would be converted to the ferrous state were it not for the protective anti-oxidant protein caeruloplasmin. 3. The ferrous-ion-oxidizing activity of caeruloplasmin rapidly converts ferrous ions back to the less reactive ferric state so that the...

a total number of 218 cerebrospinal fluids obtainedfrom children with aseptic meningitis iii tehran , were studied by attempts at virus isolation. all specimens were inoculated at least into three different cell systems. this investigation ended in isolation of 37 strains of viral agent, which are divided as following: 2 strains of poliovirus, 11 strains of coxsackie b virus, 8 strains of echov...

The application of the method of paper electrophoresis to the study of the serum proteins is now well established, but it has rarely been applied to the examination of the proteins of the cerebrospinal fluid (C.S.F.) and not at all to those of the fluids from cerebral cysts. Schneider and Wallenius (1951) have recorded their results in 14 cases, five of which were normal, while more recently Wa...

The Phadebact and Bactigen reagents were evaluated for detection of Neisseria meningitidis in cerebrospinal fluids. The Bactigen test yielded stronger agglutination reactions from clinical specimens and was significantly more sensitive when used with whole-cell suspensions and purified antigens.

The results of measurement of gamma globulin in the cerebrospinal fluid by electrophoresis and by an immunological technique are compared. In some fluids marked discrepancies were found. Such discrepancies, when substantiated and better understood, may have diagnostic significance.