BACKGROUND/AIM Telomerase activity is influenced by hTERT transcriptional regulation, shelterin, and posttranscriptional alternative splicing. Telomerase shelterin such as POT1 is highly correlated with various cancers. However, the profile of POT1 in cervical cancer has not been clearly identified. Therefore, it is important to identify its profile in cervical cancer biopsy tissue and normal c...

OBJECTIVES We explore the clinical potential of reflectance and fluorescence confocal microscopy to image the morphologic and biochemical changes associated with precancer, in order to aid in the detection and diagnosis of cervical dysplasia. METHODS Cervical epithelial tissue samples imaged ex vivo or in vivo were obtained from M. D. Anderson Cancer Center and Lyndon B. Johnson Hospital in H...

Results from epidemiologic studies suggest that a carotenoid-rich diet may reduce risk for cervical cancer, possibly by inhibiting the progression of cervical intraepithelial neoplasia, a preneoplastic lesion of the cervical tissue. Laboratory studies suggest that the mechanism may be linked to the metabolism of carotenoids to retinoic acid or retinoic acid–like compounds, which has been hypoth...

background and objective: to estimate the risk of human papilloma virus (hpv) infection for cervical malignancies, we conducted a case-control study in southern iran (hormozgan province). materials and methods: for this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of cervic...

The mechanical integrity of cervical tissue is crucial for maintaining a healthy gestation. Altered tissue biochemistry can cause drastic changes in the mechanical properties of the cervix and contribute to premature cervical dilation and delivery. We present an investigation of the mechanical and biochemical properties of cervical samples from human hysterectomy specimens. Three clinical cases...

Cervical cancer tissue analysis has been carried out using Raman Spectroscopy. The purpose of this study was to determine the effect differences in power level and exposure time on spectrum pattern that can be used as a standard distinguish normal cervical patterns. This histological preparations cancerous tissue. were made Anatomical Pathology Laboratory Sanglah Hospital Bali Branch Indonesian...

The aim of the present study was to identify novel methylation markers for cervical cancer screening and to test the clinical application of the most promising biomarker in cervical scrapings. Methylated-CpG island recovery assay-based microarray analysis was carried out on a discovery set consisting of cervical cancer tissue and normal cervical t...

  Background and Objective: To estimate the risk of human papilloma virus (HPV) infection for cervical malignancies, we conducted a case-control study in southern Iran (Hormozgan province). Materials and Methods: For this purpose,52 paraffin embedded blocks with exact diagnosis of cervical carcinoma(50 carcinomas and 2 carcinomas in situ) from 2001 to 2006 and 52 praffin embedded blocks of ce...

Background: Cervical spondylosis is a degenerative process involving changes in soft tissue and bone of intervertebral discs. Objective: To evaluate wrestling induced cervical spondylosis. Methods: 83 male wrestlers with the age range of 15 to 55 were randomly studied against 79 non-wrestlers of the same age. Clinical and radiological assessments were carried out and recorded in both groups. Wr...

Cervical agenesis or dysgenesis is an extremely rare congenital anomaly. Conservative surgical approach to these patients involves uterovaginal anastomosis, cervical canalization, and cervical reconstruction. In failed conservative surgery, total hysterectomy is the treatment of choice. Success of reconstructive surgery depends on the amount of cervical tissue available. Hence, congenital absen...