OBJECTIVES The Burkholderia cepacia complex (Bcc) species are important opportunistic pathogens with intrinsic antibiotic resistance. They are also well known as contaminants of disinfectants, yet their biocide susceptibility has not been studied in detail. We investigated Bcc biocide susceptibility and correlated it to their taxonomy, antibiotic susceptibility and ability to form biofilms. M...

Salts are transduced by at least 2 mechanisms: (a) antagonized by amiloride and (b) antagonized by cetylpyridinium chloride (CPC). The authors report on 4 behavioral experiments in rats that characterize the orosensory properties of CPC itself as well as its effect in suppressing the intensity of NaCl and KCl taste. Experiments 1 and 2 indicated that CPC has a quinine-like taste quality. Experi...

173.345 Chloropentafluoroethane. 173.350 Combustion product gas. 173.355 Dichlorodifluoromethane. 173.356 Hydrogen peroxide. 173.357 Materials used as fixing agents in the immobilization of enzyme preparations. 173.360 Octafluorocyclobutane. 173.368 Ozone. 173.370 Peroxyacids. 173.375 Cetylpyridinium chloride. 173.385 Sodium methyl sulfate. 173.395 Trifluoromethane sulfonic acid. 173.400 Dimeth...

Serratia marcescens is an important opportunistic pathogen in hospitals, where quaternary ammonium compounds are often used for disinfection. The aim of this study is to elucidate the effect of a biocide on the emergence of biocide- and antibiotic-resistant mutants and to characterize the molecular mechanism of biocide resistance in Serratia marcescens. A quaternary ammonium compound-resistant ...

A method is presented for the decontamination, liquefaction, and concentration of sputum specimens that are in transport more than 24 h. The method is inexpensive, and culture results compare well with those obtained with the accepted N-acetyl-L-cysteine and sodium hydroxide method for the isolation of tubercle bacilli. The working solution, 1% cetylpyridinium chloride and 2% sodium chloride, i...

The effect of several surfactants on the formation of the fluorescent ternary complex oxalate-Alizarin Red S-zirconium(IV) has been studied. In weakly acidic medium and in the presence of cationic surfactants, such as cetylpyridinium chloride, total complex formation is achieved, whereas in aqueous medium or in the presence of non-cationic micelles no significant changes are obtained in compari...

The isolation of the principal glycoprotein from human gastric aspirates and the determination of its carbohydrate and amino acid composition is described.Ninety-nine individual gastric aspirates were investigated. Eighty-two were eluted on Bio-gel P150 and the carbohydrate and amino acid composition of each non-retarded fraction was determined. Fifteen of these non-retarded fractions were chro...

PURPOSE To evaluate using digital plaque image analysis the antiplaque efficacy of oral care regimens including use of antimicrobial toothpaste in combination with antimicrobial mouthrinse. METHODS 16 subjects completed the study protocol including: (1) initial treatment phase, all subjects used a standard sodium fluoride dentifrice with 2x/day brushing, (2) second treatment phase, subjects w...

Purpose. To evaluate the effects of a novel mouth rinse containing 0.07% high bioavailable cetylpyridinium chloride (Crest Pro-Health Rinse) on the development of gingivitis and plaque versus a placebo control over a period of 6 months. Methods. This was a randomized, 6-month, placebo-controlled, parallel groups, double -blind, single center clinical trial. One hundred thirty-nine generally hea...