in recent years, many changes have been observed in buying culture of customers and developing chain stores in iran. moreover, need to be more competition in business environments made necessary the stablishment of chain stores, the creation of competitive advantage and long relations to the costumers. regular marketing is a response to stores requirement when establishing such a win-win long r...

One of the main issues on task planning of the enterprises with several production sites is how they can reassign tasks when a part of the supply chain is stopped. In this case, a good re-schedule, involving parts from supply chains from other sites, could imply to reduce overall costs. In this paper, we propose a cooperative system to re-schedule a network chain. The algorithm proposed is desc...

The supply chain represents the critical link between the development of new product and the market in pharmaceutical industry. Over the years, improvements made in supply chain operations have focused largely on ways to reduce cost and gain efficiencies in scale. In addition, powerful regulatory and market forces have provided new incentives for pharmaceutical firms to basically rethink the wa...

This paper considers a new class of discrete event systems under partial observations. The problem is presented within the background of a manufacturing process where workpieces are loaded and transported, and this process is controlled with the partial information collected by sensors. The model extracted is novel because the observation of an event does not only depend on an event itself, but...

The relative efficacy of intervention policies, aimed at stimulating development of antibiotics, can be estimated using Agent Based simulation. We propose that antibiotics development can be modeled as Markov Chains with time and cash loaded transitions, and that many intervention policies can be modeled as alterations to the stochastic distributions of said Markov Chains. Through the combinati...

Throughout history the most sacred, the most fantastic, the most prosaic properties have been attributed to blood. Today medical and technical advances have made blood a therapeutic resource of extraordinary importance and, thus far, an irreplaceable one. A safe, ample blood supply is a cornerstone of any health care system, and the lifeline of that supply is its donors. Donors can be divided i...

The supply chain represents the critical link between the development of new product and the market in pharmaceutical industry. Over the years, improvements made in supply chain operations have focused largely on ways to reduce cost and gain efficiencies in scale. In addition, powerful regulatory and market forces have provided new incentives for pharmaceutical firms to basically rethink the wa...

The idea in the Heat-Bath chain is that each time we “re-randomize” an element of the current configuration with respect to π conditioned on the rest of the configuration. For example, in a spin-system we re-randomize the spin of a particle conditioned on the spin of the rest of the particles. This chain is typically used to generate random samples from spin systems. It is also straightforward ...