Tissue regeneration is a complex process that involves a mosaic of molecules that vary spatially and temporally. Insights into the chemical signaling underlying this process can be achieved with a multiplex and untargeted chemical imaging method such as mass spectrometry imaging (MSI), which can enablede novostudies of nervous system regeneration. A combination of MSI and multivariate statistic...

Abstract The use of polyurethane membranes is inseparable from its several advantages, including the minimal energy, fewer additional chemicals, and having good chemical resistance. membrane synthesized using red seaweed biomass (PUM-RSB) in this study was used as a filter ammonia filtration process water. specific objective research to regenerate test resistance membranes, study, an acid solut...

Biocatalysis has made tremendous advances in the field of synthesis of industrially important products and intermediates. Cofactors are an important part of many enzymes which are involved in biocatalysis. These cofactors are expensive and stoichiometric additions are not economically feasible. This necessitates the in situ cofactor regeneration in biocatalytic processes. Various methods of reg...

Identifying the molecular pathways that are required for regeneration remains one of the great challenges of regenerative medicine. Although genetic mutations have been useful for identifying some molecular pathways, small molecule probes of regenerative pathways might offer some advantages, including the ability to disrupt pathway function with precise temporal control. However, a vertebrate r...

It has been widely reported that chemical, structural or mechanical signals of biomaterials can impact cell behaviors and tissue regeneration, but few studies have investigated the effects of biomaterial signals on cell–cell interactions although communications between cells are critical for tissue regeneration. Our recent studies have shown that chemical signals of bioglass (BG) can stimulate ...

Hepatocytes in adults are in a nonproliferative state but they have high capacity to regenerate within few hours after an injury. After partial hepatectomy or chemical injury, hepatocytes undergo a synchronized multistep process consisting of priming/initiation, proliferation, and termination. These distinct steps are essential for restoring the structure and functions of liver. The mechanisms ...