Pichia anomala WC 65 secretes a toxin that is inhibitory to a variety of yeasts, including strains of the animal pathogen Candida albicans. The toxin was purified to homogeneity by ultrafiltration, ethanol precipitation, ion-exchange chromatography with a Mono Q column, and gel permeation chromatography with a Superose 12 column. The toxin had a molecular weight of 83,300 as determined by elect...

Background: Aspergillus flavus is the most important fungus for production of Aflatoxin B1 (AFB1). This study evaluated the ability of gamma rays (GRs) and electron-beam irradiation (EBI) to counteract the deleterious effects of aflatoxin B1 (AFB1) in a chicken model. Methods: Overall, 168 one-day-old male Coturnix quails were assigned to eight treatments for 42 d in Tehran, Iran, in 2010 and ...

introduction: clostridium difficile is the etiologic agent of several infections such as pseudomembranous colitis in human. these diseases are frequently associated with antibiotic useage but many infections with this organisms are seen without antibiotic administration. in addition it is believed that clostridium difficile is one of the most important bacteria involved in acquired hospital inf...

In this study, we demonstrate that botulinum toxin can be used to chemically denervate muscles to test functional hypotheses. We injected research-grade type A botulinum toxin complex into pectoral fin abductors (abductor superficialis) of green sunfish (Lepomis cyanellus) to determine whether chemical denervation would eliminate the ability of a particular muscle to contribute to overall pecto...

The metabolic pathway of T-2 toxin in Curtobacterium sp. strain 114, one of the T-2 toxin-assimilating soil bacteria, was investigated by thin-layer and gas-liquid chromatographic analyses. T-2 toxin added to the basal medium as a single carbon and energy source was biotransformed into HT-2 toxin and an unknown metabolite. Infrared, mass spectrum, proton magnetic resonance, and other physico-ch...

Introduction: Chlorpyrifos is an organophosphorus pesticide that is commonly used in agriculture. This toxin is harmful to a wide range of organisms, including living organisms, useful arthropods, fish, birds, humans, animals, and plants. There are many physical, chemical, and biological methods for the removal of organophosphorus pesticides from ecosystems, among which biodegradation is prefer...

Nat. Chem. Biol. 9, 475–484 (2013); published online 18 July 2013; corrected after print 19 December 2013 In the version of this Review Article initially published, a double bond was missing from the chemical structure of the cyclooctene on the left side of the reaction arrow in Figure 1e. The chemical structure has been corrected in the HTML and PDF versions of the article. erratum Designer ba...

INTRODUCTION THE CHEMICAL THREAT AND ENEMY CAPABILITY THE STATUS OF CHEMICAL PROLIFERATION Chemical Warfare Capabilities of Nations International Agreements and Verification Terrorism MILITARY CHEMICAL AGENTS TACTICAL AND STRATEGIC USE OF CHEMICAL WEAPONS Chemical Agent Delivery Systems Physical Properties of Chemical Agents Strategic Concerns in the Use of Toxins Choice of Agent and Delivery S...