to determine the addition of value of neoadjuvant, concurrent and adjuvant chemotherapy to radiation in the treatment of nasopharyngeal carcinoma with regard to the overall survival (os) and disease free survival (dfs) within a six year period in tehran cancer institute. files of all patients with nasopharyngeal carcinoma treated by radiotherapy with or without concurrent chemotherapy in a cura...

context to review and summarize the literature regarding the current status of postchemotherapy laparoscopic retroperitoneal lymph node dissection (pcl-rplnd) in patients with testicular germ cell tumor. evidence acquisition a comprehensive review of the english literature was performed using the pubmed database using the terms “laparoscopy” or “laparoscopic”, retroperitoneal lymph node dissect...

leiomyosarcoma is a rare entity in prostate but it is the most common type of prostate sarcomas in adult patients. in most reported series the prognosis is poor and the median survival is about 15-18 months. hereby we present a 72 years old man who received combined modality treatment including radical surgery followed by adjuvant chemotherapy and radiotherapy. he has been well for 14 months, b...

intravenous chemotherapy is an important mean for the treatment of cancers. infusion phlebitis (ph) is a common and acute complication of chemotherapy. the frequency of ph is about 70% in patients undergoing chemotherapeutic management. it can induce the pain, increase the risk of thrombophlebitis, lead to incomplete follow-up, and thereby, affect the patient’s health status. respecting the gre...

introduction: cancer and chemotherapy could decrease serum zinc level. in this study, serum zinc level was investigated at the beginning of cancer diagnosis and 3 months after chemotherapy in children with all types of cancer. method: in this cross sectional study forty-five 1-15 year old children who were newly diagnosed cancer cases (leukemia, lymphoma and solid tumor) were evaluated. patient...

background: recent researches have led to find strategies to prevent relapse and to improve survival for gastric cancer patients, including preoperative neo-adjuvant approaches. however, the efficacy of some neo-adjuvant regimens including 5-fluorouracil, cisplatin, and docetaxel have been less investigated. the present study evaluated the outcome and mid-term survival of patients with gastric ...

introduction: chemotherapeutic drugs used to treat cancer may cause nausea and emesis by inducing the release of 5-hydroxytryptamine (5-ht) in the small intestine. blockage of 5-ht 3 receptors in the small intestine by 5-ht 3 receptor antagonists might prevent the nausea and vomiting associated with chemotherapy for cancer. the aim of this study was to compare the efficacy and tolerability of t...

radiotherapy in the head and neck region and chemotherapy might give rise to oral mucositis which is a severe and painful inflammation. there is no known definite cure for mucositis. a number of studies have attempted to evaluate the effect of low-power laser on radiotherapy- and chemotherapy-induced mucositis. the present study was undertaken to evaluate the effect of low-power laser on the pr...

background : chemotherapy induced nausea and vomiting is an added distress to patients burdened by the illness. in an effort to tackle the emetogenic potential of the agents, guidelines have been proposed to maintain uniformity in prescription and improvement in patient tolerance; but their utility and practice is not consistent. the aim of this clinical audit was to assess the antiemetic.pract...

with the success achieved in the interruption of the transmission of bilharziasis by snail control in most endemic areas of iran, mass-chemotherapy has been used extensively for reducing the number of cases in various villages. niridazol was chosen for this purpose after a screening of several drugs. eight thousand eight .l1undred seventy-four cases in 259 localities were treated from 1966 to t...