Wound-dressing sheet biomaterials can cover wound sites and enhance wound healing. In this study, a detailed evaluation of the factors affecting both the PEG modification percentage (PMP) in poly(ethylene glycol) (PEG)-grafted chitosan synthesis and the gelation properties of PEG-grafted chitosan was presented for constructing our novel hybrid hydrogel sheet consisting of PEG-grafted chitosan (...

Chitosan is a cationic polysaccharide with great properties and so is considered as an attractive biopolymer. However, chitosan shows its antibacterial activity only in acidic environment and this restricts its uses. So water-soluble chitosan derivatives such as carboxymethyl chitosan could be good candidates for such biomedical applications. Modified chitosan with hydrophobic functional groups...

Acrylicacid was grafted onto chitosan by using the ceric ammonium nitrate as the initiator. The effect of initiator concentration, monomer concentration, time & temperature on % G and % GE were studied. The grafted samples were characterized using FTIR, TGA, SEM and XRD methods. From the FTIR data it was ascertained that grafting has occurred considerably. The morphology of the grafted polymer ...

This work reports for the first time a straightforward solvent-free chemical procedure to gain access to Δ-1-pyrroline grafted onto multiwalled carbon nanotubes by the 1,3-dipolar cycloaddition of the mesoionic 4-methyl-2-phenyloxazol-5(4H)-one.

Ethyl Acrylate was grafted onto chitosan by using the ceric ammonium nitrate as the initiator. The effect of initiator concentration, monomer concentration, time & temperature on % G and % E were studied. The grafted samples were characterized using FTIR, SEM, atomic force microscopy AFM and XRD methods. Xray diffraction showed changes in the crystallinity pattern of chitosan after the copolyme...

The graft polymerization of acrylic acid has been carried out on poly(ethylene terephthalate) (PET) monofilament to introduce carboxylic acid groups. The filament is treated with oxygen plasma for the introduction of peroxides and subsequently grafted with acrylic acid. The influence of monomer concentration, plasma exposure time and reaction temperature on the degree of grafting has been inves...

Chitosan/multiwalled carbon nanotube nanocomposite has been successfully synthesized by the chemical method. The prepared nanocomposite was characterized using XRD, FTIR and HRTEM. The XRD pattern of the nanocomposite shows the presence of planes corresponding to both chitosan and MWCNT and the absence of impurity phases. The semi-crystalline nature of chitosan is also evident from the obtained...

Purpose: To formulate and evaluate pH-sensitive controlled release cefixime microspheres based on crosslinked chitosan and acryl amide-grafted-poly ethylene glycol Method: pH sensitive interpenetrating network (IPN) cefixime microspheres based on chitosan, its grafted copolymer, and hydrolyzed grafted copolymer were prepared by precipitation and crosslinking methods. The formulations were chara...

Combining mucoadhesive characteristics of a biodegradable polymer such as chitosan with the potential to enhance drug release by increasing the solubility of poorly water-soluble drugs has great potential for pharmaceutical technology and drug delivery design. Polymeric delivery systems have been extensively researched in an attempt to achieve modified drug release. Cyclodextrins (CD) offer an ...

In this study, three pyrimethanil grafted chitosan (PML-g-CS) derivatives were obtained. The structures of the conjugates were confirmed by FT-IR, (1)H NMR, and EA. The grafting ratios were measured by HPLC. Antifungal properties of pyrimethanil grafted chitosan (PML-g-CS) derivatives against the plant pathogenic fungi Rhizoctonia solani and Gibberella zeae were investigated at concentrations o...