BACKGROUND Anniston, Alabama, is the site of a former Monsanto plant where polychlorinated biphenyls (PCBs) were manufactured from 1929 until 1971. Residents of Anniston are known to have elevated levels of PCBs. The objective of the study was to test the hypothesis that levels of the various lipid components (total cholesterol, LDL cholesterol, HDL cholesterol, triglycerides) are differentiall...

Pesticides are a group of chemicals made for the purpose of killing or otherwise deterring “pest” species. The word pesticide may refer to insecticides, herbicides, fungicides, or other pest control formulations. Pesticides are inherently toxic and often associated with adverse health effects in non-target organisms.1 Organochlorine pesticides are a large class of multipurpose chlorinated hydro...

An important advance in aquatic ecotoxicology is the development and application of biomimetic sampling technology for hydrophobic contaminants. In this paper, accumulation kinetics of five organochlorinated pesticides, i.e. hexachlorobenzene, lindan, aldrin, heptachlor epoxide and 4,4'-DDT, by triolein-containing semipermeable membrane device (triolein-SPMD) and by fish (rainbow trout) were co...

BACKGROUND Exposure to persistent organic pollutants (POPs) is known to increase risk of diabetes. OBJECTIVE To determine which POPs are most associated with prevalence of diabetes in 601 Akwesasne Native Americans. METHODS Multiple logistic regression analysis was used to assess associations between quartiles of concentrations of 101 polychlorinated biphenyl (PCBs) congeners, congener grou...

Mean serum levels of polychlorinated biphenyls (PCBs) in U.S. population groups without occupational exposure to PCBs are usually between 4 and 8 ng/mL, with 95% of individuals having serum PCB measurements of less than 20. Subpopulations consuming fish taken from contaminated waters, such as Lake Michigan and near Triana, AL, have mean serum PCB levels several times those found in other genera...

This study investigated levels and distribution pattern of chlorinated organic compounds (COCs) otherwise known as organochlorine pesticides in sediment samples at downstream of Aiba watercourse in Iwo, South-western Nigeria. Soxhlet extraction method followed by GC-ECD analysis were used to ascertain levels of COCs in the sediment samples collected from four different locations along the strea...

ORGANOHALOGEN COMPOUNDS – Volume 66 (2004) 246 Introduction Pesticide residues in food present a potentially serious and significant cause for concern . Many pesticides have been associated with significant health effects to the nervous and endocrine systems and some have been deemed carcinogenic . There are many well-established techniques for pesticide analysis. However, commercial pesticide ...

The majority of cases of aplastic anemia, a rare previously lethal disease, are of unknown etiology. Nevertheless, for the past 3 decades, case reports and case series of aplastic anemia have suggested an etiologic association between aplastic anemia and pesticide exposure. A review of the medical literature, including basic science literature, confirms a possible etiologic association between ...