نتایج جستجو برای: chloro
تعداد نتایج: 19553 فیلتر نتایج به سال:
Mixed crystals of 1-(4-chlorophenylsulfonyl)-2,5-dimethyl-1 H -benzimidazole and 1-(4-chlorophenylsulfonyl)-2,6-dimethyl-1 (ratio 0.707:0.293; two molecules in the asymmetric unit), 0.707C 15 13 ClN 2 O S·0.293C S, ( I ), 2- n -butyl-1-(4- tert -butylphenylsulfonyl)-5-chloro-1 -butylphenylsulfonyl)-6-chloro-1 [ratio 0.731 (2):0.269 (2); one molecule unit], 0.731C 21 25 S·0.269C II were obtained...
this research evaluates the efficiency of nanosized zno in the catalytic ozonation of 4-chloro-2-nitrophenol and determines the effect of ph on heterogeneous catalytic ozonation. the combined use of ozone and zno catalyst leads to conversion of 98% 4-chloro-2-nitrophenol during 5 min. in addition, it was found that in zno catalytic ozonation, the degradation efficiency of 4-chloro-2-nitrophenol...
Reaction of thionyl chloride with 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid 1 gave acid chloride 2. Compound 2 was reacted with glycine and D-glutamic acid to afford 2-(7-chloro-1-cyclopropyl-6-fluoro-4-oxo-1,4- dihydroquinoline-3-carbonyl) aminopantandioicacid 3a and 2-(7-chloro-1-cyclopropyl-6- fluoro -4- oxo-1,4-dihydroquinoline-3-carbonyl)aminoacetica...
(S)-1-chloro-2-heptanol is an enantiopure chemical of great value that can synthesize Treprostinil for treating primary pulmonary hypertension. In this work, a new strain B-36, capable asymmetric reduction 1-chloro-2-heptanone to (S)-1-chloro-2-heptanol, was screened and identified as Curvularia hominis B-36 (CCTCC M 2017654) based on the morphological internally transcribed spacer (ITS) sequen...
Treatment of 1-(5-bromo-2-chloro-6-methylpyrimidin-4-yl)-1-methylhydrazine with dimethylthiocarbamoylchloride gave 7-chloro-N,N,1,5-tetramethyl-1H-pyrimido[4,5-e][1,3,4]thiadiazin-3-amine in basic acetonitrile. The latter compounds were reacted with secondary amines in boiling ethanol to afford the related 7-amino derivatives.
The inability to meet the desired outcomes of anticancer treatment and decrease in success bacterial fungal infections accelerated research these areas. Our group has conducted numerous studies, especially on benzimidazole ring systems’ antiproliferative antimicrobial activities. In this study, activity compounds was tested against A549, A498, HeLa, A375, HepG2 cancer cell lines by MTT assay. A...
Sustainable methods for producing enantiopure drugs have been developed. Chlorohydrins as building blocks several β-blockers synthesized in high enantiomeric purity by chemo-enzymatic methods. The yield of the chlorohydrins increased use catalytic amount base. reason this was found to be reduced formation dimeric by-products compared higher concentration An overall reduction reagents and reacti...
A one-pot synthesis and X-Ray structural characterization of new highly substituted-allyl carbamates
A one-pot synthesis of new variously substituted γ-chloro-γ, β-allylic carbamates have been carried out starting from β-chloro-α, β-unsaturated aldehydes. The and the corresponding intermediates, alcohols, were fully characterized by (1H 13C) NMR, IR HRMS spectroscopic techniques. crystal structures two allylic carbamates, established single-crystal X-ray diffraction.
The participation of large-conductance Ca2+ activated K+ channels (BKs) in chloroquine (chloro)-induced relaxation of precontracted airway smooth muscle (ASM) is currently undefined. In this study we found that iberiotoxin (IbTx, a selective inhibitor of BKs) and chloro both completely blocked spontaneous transient outward currents (STOCs) in single mouse tracheal smooth muscle cells, which sug...
Overexpression of mutant p53 in cancer cell inactivates the pathways to execute apoptosis and cycle arrest. This study aimed synthesize new kardiena derivative compound, 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-2-one, reactivate Characterization synthetic compound employing melting point, IR, EI-MS, 1H-NMR, 13C-NMR spectra revealed 3-carbethoxy-4(3’-chloro-4’-hydroxy)phenyl-but-3-en-...
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