نتایج جستجو برای: choroid plexus
تعداد نتایج: 16851 فیلتر نتایج به سال:
1. Abstract 2. Introduction 3. Structure and Functions of Choroid Plexus 3.1. Structure of choroid plexus 3.2. Functions of choroid plexus 3.3. Composition of cerebrospinal fluid 4. Ageing of Choroid Plexus 4.1. Anatomical modifications in ageing 4.2. Functional alterations in ageing 4.3. Modification of cerebrospinal fluid in ageing 5. Choroid Plexus and Alzheimer’s Disease 5.1. Anatomical alt...
Introduction Choroid plexus tumors (CPT) are defined as papillary neoplasms originating from the epithelium of the choroid plexus within the ventricles. They are classified into mainly two types: -benign choroid plexus papillomas (CPP) (World Health Organization WHO grade I) and -choroid plexus carcinomas (WHO grade III). [1,3] An intermediate group lies between the two groups and is referred t...
Although heavy metal ions are known to be toxic to the central nervous system (CNS), the mechanisms by which the CNS may protect itself from initial challenges of such toxic ions is unknown. The choroid plexus is the principal site of formation of the cerebrospinal fluid (CSF) which bathes the brain. We have determined in rats and rabbits that after intraperitoneal administration of lead, cadmi...
Background: The most common mechanism associated with the development of choroid plexus carcinoma seems to be mutation of the TP53 gene. The R337H mutation of the TP53 gene has been reported in a significant proportion of patients with choroid plexus tumors. The aim of the present study was to use immunohistochemical techniques to establish whether the presence of the R337H mutation is associat...
A sheet of choroid plexus epithelial cells extends into each cerebral ventricle and secretes signaling factors into the CSF. To evaluate whether differences in the CSF proteome across ventricles arise, in part, from regional differences in choroid plexus gene expression, we defined the transcriptome of lateral ventricle (telencephalic) versus fourth ventricle (hindbrain) choroid plexus. We find...
Choroid plexus papilloma is a rare benign tumor accounting for 0.5% of all intracranial tumors. The majority of choroid plexus papillomas occur during the first 2 years of life in the ventricular system. Moreover, dense calcification of the tumor is uncommon. We report an adult case of densely calcified, atypical choroid plexus papilloma that originated from the cerebellopontine angle without c...
Using MR imaging, the authors detected 23 cases of intracranial lipomas, among which were three cases of solitary choroid plexus lipomas. All the lipomas were located in the choroid plexus at the trigone. One of the three solitary choroid plexus lipomas was very small and could not be detected using CT. The authors believe that solitary choroid plexus lipomas are not as rare as was previously t...
The choroid plexus, located in brain ventricles, has received surprisingly little attention in clinical neuroscience. In morphometric brain analysis, we serendipitously found a 21% increase in choroid plexus volume in 12 patients suffering from complex regional pain syndrome (CRPS) compared with age- and gender-matched healthy subjects. No enlargement was observed in a group of 8 patients suffe...
Infiltrating T cells and monocyte-derived macrophages support central nervous system repair. Although infiltration of leucocytes to the injured central nervous system has recently been shown to be orchestrated by the brain's choroid plexus, the immunological mechanism that maintains this barrier and regulates its activity as a selective gate is poorly understood. Here, we hypothesized that CD4(...
The pathogenesis of choroid plexus papillomas, intraventricular papillary neoplasms most often occurring sporadically in children and young adults, remains poorly understood. To identify pathways operative in the development of choroid plexus papillomas, gene expression profiles obtained from laser-microdissected human choroid plexus papilloma cells (n = 7) were compared with that of normal cho...
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