Background: The prevalence of hepatitis B and C in Iranian children with chronic kidney disease is limited. Therefore, the present study intends to assess the prevalence of hepatitis B and C in children with chronic kidney disease (CKD).Method: The present study is a historical cohort study which was conducted in a window period of 25 years in Children’s Medical Center in Tehran, 1991-2016. Dat...

background despite significant advances in the treatment of chronic hepatitis c in the past decades, factors which can affect response rates to combination therapy; peginterferon and ribavirin, are still under study and reaching sustained virological response (svr) is affected by several different factors. objectives to investigate predictor factors contributing to svr in iranian patients. pati...

background: hepatitis c virus (hcv) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. in this study we aimed to evaluate the effects of pegylated interferon alfa-2a (peg-ifn a-2a) in reducing serum alt and eradicating serum hepatitis c virus (hcv) rna in hcv infected polytransfused thalassemic patients. materials and methods: a cohort of 51 hcv-...

background various aspects of adherence to hcv treatment such as frequency, risk factors as well as causes of non-adherence, and its real role in clinical and virological outcome of the infected patients have remained largely unknown. objectives the current study aimed to evaluate patients’ adherence to anti-hcv medications in iran. materials and methods from october 2010 to march 2011, socio-d...

results patients who attained sustained virological response had a less risk (85%) for all-cause mortality and about 63% reduced risk of hepatocellular carcinoma incidence than those who did not achieve sustained virological response. based on deeply analysis, the stage of liver fibrosis was a risk factor at baseline for the incidence of hepatocellular carcinoma. conclusions sustained virologic...

context several risk factors play the role in the development of hepatocellular carcinoma (hcc) from which chronic hepatitis b and c infections are the most important ones. dna integration of hepatitis viruses alters the function of critical genes promoting malignant transformation of virus-infected liver cells. evidence acquisition there are remarkable geographic differences in prevalence of c...

objectives: patients with hepatitis c virus infection are at high risk of getting hepatitis a virus. hepatitis a virus is an important widespread virus that usually causes more severe medical consequences in patients with chronic liver disease. the purpose of this study was to evaluate prevalence of hepatitis a virus antibody in patients with chronic hcv in isfahan province, iran. methods: a cr...

background: hepatitis b virus (hbv) vaccination is a well-known, safe and effective way for protection against hbv infection; however, non-responders remain susceptible to infection with hbv. this is so important in patients with any kind of chronic liver disease, especially chronic hepatitis c virus (hcv) patients in whom acute hbv infection may lead to decompensation of liver disease. some of...

Background and Aims: Viral hepatitis is a global health problem with a high mortality rate. Recently, a new Flavi-like virus, provisionally named hepatitis G virus (HGV), has been described. HGV does not induce an immune response that is consistently detectable by using recombinant proteins from prokaryotic expression, therefore studies have been conducted by using polymerase chain reaction (...