In this study, the efficacy of bactericidal/permeability-increasing protein (BPI) was assessed in a rat model of chronic otitis media with effusion. BPI injection prevented disturbance of the mucociliary clearance system of the middle ear. Hence, it is postulated that BPI can be a new therapy for chronic otitis media with effusion.

abstract background: the children with middle ear effusion need repeated re-tympanostomies. adenoidectomy is an effective surgical intervention in the management of chronic otitis media with effusion in conjunction with in-sertion of tympanostomy tubes (tts). to find out whether tts in different positions decrease the rate of re-tympanostomies study was done. methods: the present study retrospe...

introduction:to evaluate the role of allergic-type and infectious-type cytokines in children with chronic otitis media with effusion (ome) materials and methods:we investigated serum levels of interleukins (il)-4, il-5, and il-13, along with interferon-gamma (ifn-γ) and tumor necrosis factor-alpha (tnf-α), by enzyme-linked immunosorbent assay (elisa) in 35 children with ome and 28 healthy contr...

introduction: to study the long-term complications of tympanostomy tube insertion in young children 10 years after surgery.   materials and methods: in september 2011, the medical records of all patients who had undergone myringotomy with tympanostomy tube insertion between february 2000 and march 2001 at the two general hospitals of isfahan university of medical sciences were studied. of the 9...

abstract   objective: to determine the effect of oral zinc sulfate supplementation given with coamoxiclav when compared with coamoxiclav alone for treatment of otitis media with effusion (ome). the efficacy of the drug was assessed 3 and 6 weeks after administration .   methods: in a double-blind, randomized trial 4 to 14 years old children with ome who referred to ear, nose and throat clinic, ...

objectives: the aim of this study was to compare the otitis media with effusion (ome) groups that improved when treated with adenoidectomy and ventilation tube (vt), to the group of the recurred after surgery and detect the possible role of allergy in ome. material and methods: this study was performed on two groups. the patient group consisted of 38 patients with recurrent ome with allergy an...

AIM Auditory tube dysfunction is one of the aetiological causes of otitis media. Studies suggest a correlation between otitis media with effusion and dental malocclusion. Our goal was to determine any correlation between dental malocclusion and otitis media with effusion in children with chronic upper airway obstruction due to tonsil and adenoid enlargement. MATERIALS AND METHODS This prospec...

Background: Otitis is the most common infectious disease of the ear with internal and external cranial complications. If the infection is in the middle ear, it causes otitis media. If the infection is in the external ear, it’s along with otitis externa (OE). Different types of otitis media include acute otitis media (AOM), chronic otitis media (COM) and Otitis media with effusion (OME). This st...

In the absence of any acute otological symptoms including pain and temperature, a middle ear effusion in association with hearing loss has been designated by various names, i.e. catarrhal otitis, exudation otitis, serous otitis, nonsuppurative otitis, glue ear, and currently the most fashionable terms, otitis media with effusion and secretory otitis media. A middle ear effusion without inflamma...

the middle ear is the most prevalent disease of childhood. The other areas of the temporal bone which can be contiguous with the middle ear, including the mastoid, petrousus apex and perilabyrinthine air cells, may also be involved. Otitis media can be further divided into acute otitis media (AOM) without effusion, otitis media with effusion (OME), chronic suppurative otitis media (COM) with or...