Granuloma annulare is a benign, relatively common dermatosis of childhood and young adults. Lesions typically occur on the extremities. Localized facial and periocular involvement is rare. We describe a 25- year-old woman with asymptomatic skin-color, firm, and papular lesions on both periocular areas since 6 months ago. Histological examination revealed palisading necrobiotic granuloma, charac...

introduction: cleft lip and palate are among the most common congenital anomalies worldwide. this study was conducted in order to explore the incidence and related factors of cleft lip and/or palate (cl/p) among live births in mashhad, north-eastern iran.   materials and methods: in this cross-sectional study, records of 28,519 infants born between march 1982 and march 2011 at three major hospi...

results no significant difference was found between the groups regarding bmht rs3797546 gene polymorphism. the c allele was not associated with ns-cl/p (or = 1.27, 95% ci = 0.85-2.79, p = 0.690). conclusions our data suggested that bmht rs3797546 gene polymorphism was not associated with risk/ protection for ns-cl/p in a sample of iranian population. larger studies are required to validate our ...

Introduction: Orofacial clefts are among the most common congenital anomalies. Patients presenting with orofacial clefts often require surgery or other complex procedures. A cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. The reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnost...

background: one of the most common anomalies in newborn infants is cleft lip and/or cleft palate (cl/p). in spite of several studies about the prevalence of this, no investigation evaluated this prevalence in the west and north-west of iran. with due attention to different ethnic groups in this area, the aim of this study is to investigate whether the distribution of cl/p live births varies reg...

introduction: orofacial clefts are among the most common congenital anomalies. patients presenting with orofacial clefts often require surgery or other complex procedures. a cleft lip or palate can be a single anomaly or a part of multiple congenital anomalies. the reported prevalence of cleft disease and associated anomalies varies widely across the literature, and is dependent on the diagnost...

introduction : surgical repair of cleft palate with a bony bridge may offer some distinct advantages including a lower rate of fistula formation. the goal of this study was to evaluate the feasibility of surgically inducing cleft palate and reconstruction of the cleft with the use of bone morphogenetic protein-2 (bmp-2) in sheep. materials and methods : in the control group (two sheep), the cle...

some lesions in the oral cavity and mostly on gingiva have predominant predilection towards females, and mostly occur in the first four decades of life when changes in sex hormone levels in blood are obvious. the present study aimed to investigate the presence and distribution of estrogen and progesterone receptors in peripheral giant cell granuloma (pgcg), pyogenic granuloma (pg) and periphera...

Objectives: One of the factors predicting language impairments is an early limited lexicon in children. An early limited lexicon can also lead to limited performances in other language areas. This study was aimed to examine receptive and expressive vocabulary in 8-16 month-old children with cleft lip and palate as a predictor of development in other language areas. Materials: The MacArthur-Bat...

orofacial clefts, including cleft lip with or without cleft palate (cl (p)), are common congenital malformations, second only to clubfoot in frequency of occurrence. the epidemiology and genetics of this disorder have been studied extensively in various countries by several investigators. the objective of this study is to assess the epidemiology and some genetic aspects of orofacial clefting at...