A sensitive and precise RP-HPLC method has been developed for the simultaneous estimation of clidinium bromide (CDB) and chlordiazepoxide (CDZ) in pure and pharmaceutical formulations. The separation was achieved on a Nucleodur C8 (250 × 4.6 mm i.d., 5 μm particle size) column at 25°C. CH3CN-MeOH-NH4OAc 0.1M (30 : 40 : 30, v/v/v) was used as the mobile phase at a flow rate of 1.0 mL min(-1) and...

The introduction of sustainable development concepts to analytical laboratories has recently gained interest, however, most conventional high-performance liquid chromatography methods do not consider either the effect of the used chemicals or the amount of produced waste on the environment. The aim of this work was to prove that conventional methods can be replaced by greener ones with the same...

Objectives: Older people are more prone to chronic diseases and being treated than other age groups; as a result, they use drugs that may be inappropriate lead adverse drug reactions. This study aimed determine the rate of using Beers criterion among elderly in Amirkola City. Methods & Materials: The current descriptive-analytical is part comprehensive plan "Study health status City” AHAP" ...

The method of competition kinetics, which measures the binding kinetics of an unlabeled ligand through its effect on the binding kinetics of a labeled ligand, was employed to investigate the kinetics of muscarinic agonist binding to rat brain medulla pons homogenates. The agonists studied were acetylcholine, carbamylcholine, and oxotremorine, with N-methyl-4-[3H]piperidyl benzilate employed as ...

       The goal of this study is to identify the types of potentially inappropriate drugs prescribed by the medical specialists of Isfahan province to elderly patients. A number of 31,254 randomly selected prescriptions from medical specialists of Isfahan province were reviewed for elderly patients who were insured by the Social Security Organization. Three thousand and seven prescriptions were...

the goal of this study is to identify the types of potentially inappropriate drugs prescribed by the medical specialists of isfahan province to elderly patients. a number of 31,254 randomly selected prescriptions from medical specialists of isfahan province were reviewed for elderly patients who were insured by the social security organization. three thousand and seven prescriptions were identi...