Keishibukuryogan (KBG; Guizhi-Fuling-Wan in Chinese) is one of the Kampo (Japanese traditional) medicines used to treat patients with climacteric syndrome. KBG can be used by patients who cannot undergo hormone replacement therapy due to a history of breast cancer. We evaluated whether cytosine-adenine (CA) repeat polymorphism of the estrogen receptor β gene can be a predictor of the beneficial...

OBJECTIVE to assess the therapeutic efficacy and safety of oral estriol for the treatment of climacteric symptoms in postmenopausal women. METHODS 68 postmenopausal women with climacteric symptoms received oral estriol, 2 mg/day, daily for 12 months. We evaluated the degree of climacteric complaints with estriol therapy; serum levels of gonadotropins, estradiol (E2) and lipids; biochemical ma...

CONTEXT AND OBJECTIVE Climacteric symptoms may vary between different countries and cultures. Socioeconomic factors and climate may be implicated. The aim of this study was to identify climacteric symptomatology among very low-income Brazilian women, living in a hot and humid region. DESIGN AND SETTING This cross-sectional population-based study was conducted in Cuiabá, at Júlio Müller Univer...

PURPOSE The purpose of this study was to construct a measurement instrument for climacteric symptoms among Korean and Japanese women. METHODS From Dec. 1st of 2003 to March 30th of 2004, in-depth interviews were made with 26 women (15 in Jinju, Korea and 11 in Nagasaki, Japan) aged from 45 to 59 years who had not taken hormone replacement therapy to relieve the climacteric symptoms. A draft q...

A total of 28 postmenopausal women who had menopause of less than 2 years duration with one or other climacteric symptoms, were included in the study. It was observed that maximum number of cases presented with vasomotor instability and psychological symptoms. They were evaluated clinically. Serum hormone levels (FSH, LH, Estradiol, Progesterone) and lipid profile were done at the time of prese...

OBJECTIVE To evaluate the efficacy comparison of Pueraria mirifica (PM), name in Thai is Kwao Kruea Khao, against conjugated equine estrogen (CEE) with/without medroxyprogesterone acetate (MPA) in the treatment of perimenopuasal women with climacteric symptoms. MATERIAL AND METHOD Perimenopausal women attending the Menopausal clinic of Hat Yai Regional Hospital were voluntarily recruited. The...

This is the first study to assess prevalence of symptoms premenstrual dysphoric disorder (PMDD), episodes postpartum depression (PPD) after childbirth, and climacteric mood in Attention-Deficit/Hyperactivity Disorder (ADHD). 209 consecutive women (18–71 years) with ADHD completed PMDD chapter Neuropsychiatric Interview Plus version 5.0.0 PMDD, Edinburgh Postnatal Depression Scale PPD, Greene Cl...