Chiari I malformation may not be congenital, but may be acquired as a consequence of skull deformities and other associated intracranial factors in patients with craniosynostosis. Pfeiffer syndrome is one of the many conditions associated with Chiari I malformation. Premature fusion of multiple cranial sutures and cloverleaf skull (kleeblattschädel deformity) are often observed in the calvaria ...

Pfeiffer syndrome is a rare autosomal dominantly inherited disorder that associates craniosynostosis, broad and deviated thumbs and big toes, and partial syndactyly on hands and feet. Hydrocephaly may be found occasionally, along with severe ocular proptosis, ankylosed elbows, abnormal viscera, and slow development. Based on the severity of the phenotype, Pfeiffer syndrome is divided into three...

The rare form of skeletal dysplasia is thanatophoric dysplasia. The meaning for thanatophoric dysplasia is death bearing which is derived from Greek word. It occurs 1in 20,000 to 50,000. It is mainly due to mutations in the fibroblast growth factor receptor 3gene. Features of thanatophoric dysplasia are frontal bossing, prominent eyes, narrow thorax, protruded abdomen and bowed legs. The knowle...

Pfeiffer syndrome (PS) is an autosomal dominant condition comprising bilateral coronal craniosynostosis, midface hypoplasia with a beaked nasal tip, and broad and medially deviated thumbs and great toes [1]. It is a clinically variable disorder and has been divided into three subtypes by Cohen in 1993 [2]. Originally, it was described in eight persons from three generations in a pedigree consis...

We report the detections of the hyperluminous galaxy IRAS F15307 +3252 at z = 0.93 and of the Cloverleaf quasar, H 1413+117 at z = 2.56, in the mid infrared using ISOCAM. The spectrum near 10 μm (observed wavelength) joins smoothly with the data taken from the ground or with the IRAS satellite. We have detected none of the infrared features attributed to PAHs. For F15307 +3252, the mid-IR emiss...

Seldom research work has been done about cloverleaf junction expression in a 3-dimensional city model (3DCM). The main reason is that the cloverleaf junction is often in a complex and enormous construction. Its main body is bestraddle in air, and has aerial intersections between its parts. This complex feature made cloverleaf junction quite different from buildings and terrain, therefore, it is...

The bovine enterovirus (BEV) serotypes exhibit unique features of the non-translated regions (NTRs) which separate them from the other enteroviruses. Their most remarkable property is an additional genome region of 110 nt located between the 5'-cloverleaf and the internal ribosome entry site (IRES). This genome region has the potential to form an additional cloverleaf structure (domain I*) sepa...