Nyctaginaceae, the Four O'Clock Family, is a family of around 33 genera and 290 species and it is well known for its ornamental and medicinal values. Pisonia grandis R.Br is one such medicinal plant of the Nyctaginaceae family with a high medicinal potential and is freely available in India. The leaves stem and roots of this plant are extensively used by the tribals in the preparation of severa...

The present study was taken up to evaluate the efficacy of Trigonella foenum graecum and Coccinia indica individualy and in combination in streptozotocin induced diabetic rats for a period of 90 days. The various groups in this study included normal control (Group-I), diabetic control (Group-II), diabetic rats treated with Trigonella foenum graecum (Group-III), diabetic rats treated with Coccin...

In March 2021, severe signs of powdery mildew were observed on leaves and stems Coccinia grandis in the Manchar, Pune District, Maharashtra state, India. Based morphological examination, phylogenetic analyses, pathogenicity test, causal agent was identified as Golovinomyces tabaci. To our knowledge, this is first record G. tabaci infecting C. Previously, had only been reported from Taiwan Thail...

Biomaterials with antibacterial activity are widely developed for the treatment of bone infection. In the present study, hydroxyapatite (HAp) nanorods were prepared by green synthesis using Azadirachta indica and Coccinia grandis leaf extract. The prepared samples were characterized by various characterization techniques and the results indicate that the prepared samples are constituted of phas...

The present study was aimed at investigating the antioxidant activities of the various fractions of the hydromethanolic extract of the leaves of Coccinia grandis L. Voigt. (Cucurbitaceae). The antioxidant activities of the fractions have been evaluated by using nine in vitro assays and were compared to standard antioxidants such as ascorbic acid, alpha-tocopherol, curcumin and butylated hydroxy...

This research aims to investigate the hypoglycemic activity of methanolic extract of Tectona grandis root in alloxan induced diabetic albino rats. A comparison was made between the action of Tectona grandis methanolic extract and a known antidiabetic drug glibenclamide (0.5mg/kg p.o).The methanolic extract of Tectona grandis linn. root was administered orally at different doses to normal rats. ...

The independent evolution of heteromorphic sex chromosomes in 19 species from 4 families of flowering plants permits studying X/Y divergence after the initial recombination suppression. Here, we document autosome/Y divergence in the tropical Cucurbitaceae Coccinia grandis, which is ca. 3 myr old. Karyotyping and C-value measurements show that the C. grandis Y chromosome has twice the size of an...

The present study was conducted to evaluate the hepatoprotective effects of an aqueous leaf extract of Coccinia grandis on carbon tetrachloride (CCl4) induced liver damage in albino rats. Wistar albino rats weighing around 180-200g were used. Toxicity was induced by using 30% CCl4 suspended in olive oil (1.0 ml/kg body wt intraperitoneal) after every 72 hrs for 3doses. The aqueous leaf extract ...

The ethnopharmacological survey has revealed that only the frontal leaves of Tectona grandis have been used for the treatment of wounds. Comparative study of the activity and phytoconstituents of the mature and the frontal leaves of Tectona grandis was carried out. Wound healing activity of both the extracts was evaluated by the excision wound model. The wound healing was 100 % on the 12 day an...