Ulcerative colitis is chronic and recurrent disease of the gastrointestinal tract with uncertain etiology and incomplete treatment options. N-methyl-d-aspartate (NMDA) receptor suppression has shown anti-inflammatory effects in vitro and in vivo. The aim of present study was to evaluate the role of dizocilpine (MK-801), a noncompetitive NMDA receptor antagonist, on TNBS (trinitrobenzene sulfoni...

Introduction: Ulcerative colitis is a chronic inflammation of the large intestine (colon). In patients with ulcerative colitis, ulcers and inflammation of the inner lining of the colon lead to symptoms such as abdominal pain, diarrhea, and rectal bleeding. Previous studies have shown that Matricaria recutita L. have a series of physiological effects for example spasmolytic, carminative, anti...

cytomegalovirus (cmv) infection can cause colitis which is usually manifested with fever, weight loss, anorexia and abdominal pain.watery diarrhea can be the only manifestation. cmv colitis usually can not be diagnosed according to the clinical findings. moreover, endoscopic appearance can exactly mimic pseudo-membranous colitis. here by, we are presenting a patient with fever and watery diarrh...

Since the ordinary tests for diagnosis chronic amebic colitis looks to be unsufficient. We try to design the following study. Our study seeks the importanc.;e of "IFA" (Indirect Immuno Fluorescent Aniti body). Among 145 patients with amebic colitis Entamoeba hystolitica observed with reapeted and specified tests. In searh of serologic tests, antibody range in 20 patients who had amebic coliti...

introduction and aims: microscopic colitis has been generally recognized as lymphocytic colitis and collagenous colitis: two inflammatory diseases of large intestine without a definite origin. the colon appears normal by colonoscopy. so, biopsy of the colonic mucosa is mandatory for diagnosis. materials and methods: as a descriptive design we assessed epidemiological, clinical and laboratory fi...

some dermatologic manifestations are common in ulcerative colitis (uc). herein, we present a 36-year-old woman with ulcerative colitis and uncommon nasal mucosa pyoderma vegetans. the patient presented to our hospital with symptoms of active colitis and a concomitant 3×4×5 cm dermato-mucosal lesion in her left nasal lumen. after surgery of the mucosal lesion, the treatment for her active coliti...

Background: Chronic diarrhea is a common problem in patients with symptoms related to gastro-intestinal tract. Some of these patients present with chronic non-bloody, watery diarrhea and no specific clinical, laboratory, or endoscopic findings. The aim of the present study was to investigate the value of histological findings in patients with chronic diarrhea who have normal or non-specific end...

Objective(s): Ulcerative colitis (UC) is a kind of complex immune disease, and a major cause of destruction of intestinal barrier and oxidative stress in this field. In this paper, glutamine (Gln) was believed to offer protection against oxidative stress injury in colitis mice.Materials and Methods: Thirty mice were randomly assigned int...

conclusions our results showed that vitamin d deficiency is more common in patients with ulcerative colitis. laboratory findings confirmed the rise of esr and crp. results our sample comprised of 32 patients with active and 32 patients with silent ulcerative colitis, and 32 age- and sex-matched healthy controls. the frequency of vitamin d deficiency was significantly higher in patients with act...